Catheter associated urinary tract infections by P. aeruginosa are related to variety of complications. Quorum sensing and related circuitry guard its virulence potential. Though P. aeruginosa accounts for an appreciable amount of virulence factors, this organism is highly unstable phenotypically. Thus, genotyping of clinical isolates of P. aeruginosa is of utmost importance for understanding th...

In Pseudomonas aeruginosa, the quorum-sensing (QS) system is closely related to biofilm formation. We previously demonstrated that 14-alpha-lipoyl andrographolide (AL-1) has synergistic effects on antibiofilm and antivirulence factors (pyocyanin and exopolysaccharide) of P. aeruginosa when combined with conventional antibiotics, while it has little inhibitory effect on its growth. However, its ...

As a ubiquitous environmental organism and an important human pathogen, Pseudomonas aeruginosa readily adapts and responds to a wide range of conditions and habitats. The intricate regulatory networks that link quorum sensing and other global regulators allow P. aeruginosa to coordinate its gene expression and cell signaling in response to different growth conditions and stressors. Upon nutrien...

This paper aims at explaining the background of persistence Pulang ka Bako marriage in Lasi area and its correlation to family resilience. research is field research. The Minangkabaunese still carry out tradition (marrying daughter father’s female sibling) Minangkabau community, especially area. considered ideal type Minangkabau. data sources were obtained from result interview with married cou...

Sansevieria trifasciata is a plant that commonly utilized in traditional medicine. The leaves of S. show antibacterial properties against Pseudomonas aeruginosa. This bacterium an opportunistic pathogen can cause serious illness humans and produce variety virulence factors responsible for bacterial pathogenesis with quorum sensing (QS) systems mediate intracellular communication. Bacteria prote...

Chronic wounds are a big challenge in contemporary society, as they lead to decrease life-quality, amputations and even death. Infections biofilm formation might occur with chronic wounds, due the higher susceptibility antibiotic multi-resistant bacteria. In this situation, novel wound dressing biomaterials needed for treatment. Thus, aim of research was evaluate possible BNC interaction tucumã...

The LasR/LasI quorum-sensing system in Pseudomonas aeruginosa influences global gene expression and mediates pathogenesis. In this study, we show that the quorum-sensing system activates, via the transcriptional regulator PA4778, a copper resistance system composed of 11 genes. The quorum-sensing global regulator LasR was recently shown to directly activate transcription of PA4778, a cueR homol...

Pseudomonas aeruginosa controls the secretion of extracellular virulence factors, including rhamnolipids and LasB elastase, by the las and rhl quorum-sensing systems. Here, we mutated the dksA gene of P. aeruginosa by insertion of an Omega-Hg cassette. The mutant displayed growth rates similar to that of the wild type in rich medium but was impaired in growth in defined minimal medium. Producti...

This paper examines health disparities in biomarkers among a representative sample of Indians aged 45 and older, using data from the pilot round of the Longitudinal Aging Study in India (LASI). Hemoglobin level, a marker for anemia, is lower for respondents with no schooling (0.7 g/dL less in the adjusted model) compared to those with some formal education. There are also substantial state and ...