We examine the problem of family size statistics (the number of individuals carrying the same surname, or the same DNA sequence) in a given size subsample of an exponentially growing population. We approach the problem from two directions. In the first, we construct the family size distribution for the subsample from the stable distribution for the full population. This latter distribution is c...

OBJECTIVE To describe the enrollment rates and characteristics of Hispanics and non-Hispanics from Kaiser Permanente Colorado invited to participate in a web-based intervention promoting increased fruit and vegetable consumption. DESIGN Hispanics were identified by the Passel-Word Spanish surname list. Characteristics associated with the likelihood of enrollment overall and by ethnicity were ...

Agriculture informationization is the inevitable trend of the world modern agricultural development, at present it is the most main bottleneck that rural informationization progress is slow in the course of Chinese rural informationization development, the last kilometer becomes a difficult problem to solve urgently. Based on the theory of participatory rural community, this article lead to ana...

This paper reviews critiques of the Human Development Report over the last twenty years. The critiques are mostly related to the choice of indicators, to high correlation of HDI components, functional form of the HDI including normalization of component indicators, aggregation vs. multiplication, and issues related to weighting. A thorough analysis of the critiques leads us to a proposal for mo...

Preference aggregation and in particular ranking are mainly studied by the field of social choice theory but extensively applied a variety contexts. Among most prominent methods for aggregation, Kemeny method has been proved to be only one that satisfies some desirable properties such as neutrality, consistency Condorcet condition at same time. Unfortunately, problem finding is NP-hard, which p...

timolol is a non-selective beta-adrenergic receptor antagonist administered for treating glaucoma, heart attacks and hypertension. in the present study, we set out to determine whether or not timolol can provoke cataract formation, thus the influence of timolol on the amyloid-type aggregation of crystallin was investigated. we then provided experimental evidence of crystallin aggregation and it...

This study was performed to assess the clopidogrel activity in inhibition of platelet aggregation in suspected angina patients on a daily dosag of 75 mg of clopidogrel for at least 7 days. This clinical trial was conducted in the outpatients department of Cardiology, Post graduate Medical Institute, Lady Reading Hospital, Peshawar from 15th October 2007 to 20th December 2007. We included 105 su...

A major problem in the formulation of therapeutic proteins is the irreversible protein aggregation. Recombinant human interferon alpha2b (rhIFN2b) has poor stability and undergoes physical degradation. The aim of this study was to investigate the effect of solution conditions on the heat-induced aggregation of rhIFNα2b. The protein was incubated for 1 h at 40°C–70°C and for up to 240 h at 50C...

A major problem in the formulation of therapeutic proteins is the irreversible protein aggregation. Recombinant human interferon alpha2b (rhIFN2b) has poor stability and undergoes physical degradation. The aim of this study was to investigate the effect of solution conditions on the heat-induced aggregation of rhIFNα2b. The protein was incubated for 1 h at 40°C–70°C and for up to 240 h at 50C...