Carcinogenic hydrocarbons induce tumors which have individually specific antigens (12). As isoantigens, these tumor-specific antigens can elicit an immune response which is primarily cell mediated (6, 11, 12) but which is unable to inhibit the primary tumor growth. Specific stimulation and active stimulation of host immune mechanisms for the therapy of primary tumors or their métastaseshave be...

BACKGROUND Human umbilical cord blood cells (HUCBCs) were used to investigate the mechanisms underlying the beneficial effects of cord blood cells in spinal cord injury (SCI). METHODS Rats were divided into three groups: (1) sham operation (laminectomy only); (2) Laminectomy+SCI+human adult peripheral blood mononucleocytes (PBMCs) (5 x 10(6)/0.3 mL); and (3) Laminectomy+SCi+HUCBCs (5 x 10(6)/...

background :many studies have reported the increase in strength of the untrained contralateral limb after unilateral training. the aim of this study was to compare the cross education effect in the young and elderly persons.   methods : in this quasi-experimental and pre-post study, 12 young people aged 28.25 ±3.11 years and 12 elderly persons (aged 73.08 ± 5.3 years) participated. the subjects...

BACKGROUND Morphine sulfate has long been used for analgesia, but clinical applications can be limited by side effects, tolerance, and potential for addiction at therapeutic doses. An agent that produces therapeutic analgesia when coadministered with low-dose morphine could have important clinical uses. The anticonvulsant agent gabapentin has been identified as having antihyperalgesic propertie...

BACKGROUND Transplantation of ex vivo expanded circulating endothelial progenitor cells (EPCs) from peripheral blood mononuclear cells improves the neovascularization after critical ischemia. However, the origin of the endothelial progenitor lineage and its characteristics have not yet been clearly defined. Therefore, we investigated whether the phenotype and functional capacity of EPCs to impr...

OBJECTIVE To establish a protocol to collect temporal-spatial gait analysis variables by use of a portable walkway system in Labrador Retrievers at a walk and to determine reference values. ANIMALS 56 healthy Labrador Retrievers. PROCEDURES 6 passes across the walkway (3 passes in each direction) were recorded. Inclusion criteria for a pass were that the dog was at a walk (velocity, 60.0 to...

OBJECTIVES Methods are needed for quantifying muscle deconditioning due to immobilization, aging, or spaceflight. Electrical impedance myography (EIM) is one technique that may offer easy-to-follow metrics. Here, we evaluate the time course and character of the change in single- and multi-frequency EIM parameters in the hind-limb suspension model of muscle deconditioning in rats. METHODS Sixt...