The ability of the physiologically essential divalent metals calcium and magnesium to inhibit the tumorigenic activities of lead and nickel towards the lungs of strain A mice was investi gated. The tumorigenic salts lead(ll) subacetate and nickel(ll) acetate were injected i.p. at their maximal tolerated doses (0.04 mmol/kg/injection of each metal) for a total of 24 injections, whenever possible...

AIM The aim of this study was to investigate the morphological and functional features of the process of spermatogenesis in the testes of male albino rats when exposed to lead acetate. MATERIALS AND METHODS Using histological, morphometric and statistical methods explored the effects of lead acetate on the process of spermatogenesis in the testes of male albino rats. Investigations were carri...

In this article, we check and develop further some postulates of the theory and mathematical modeling of combined toxic effect that we proposed earlier [1]. To this end, we have analyzed the results of an experiment on rats exposed during 6 weeks to repeated intraperitoneal injections of lead acetate, sodium fluoride or both. The development of intoxication was estimated quantitatively with 54 ...

BACKGROUND/AIM It has been reported from in vivo exposed experimental animals that paternal lead exposure reduces birth rate; however, there is limited evidence to suggest a decrease in the proportion of male births. This study investigated the role of paternal exposure to lower lead acetate doses on early embryonic development (implantation) and the sex ratio of their offspring. MATERIALS AN...

The current study aimed to investigate the curative and preventive effect of alcoholic aqueous extract Capparis spinosa leaves on histological structure kidneys some biochemical parameters male rats injected intraperitoneally with lead acetate. Biometrics included urea, creatinine, uric acid total protein levels antioxidants (T-AOX), glutathione (GSH) malondial aldehyde (MDA) assay. 40 laborato...

stereologic methods are used to abtain quantitative information about 3-dimensional structures from histologic sections. the aim of the present study was using new and unbiased stereologic techniques to investigate changes in volume and number of glomeruli after chronic lead acetate intoxication both quantitatively and in 3-dimensional spaces.lead is one of the heavy metals that has adverse eff...

Lead is a highly neurotoxic agent that particularly affects the developing central nervous system. In the current study we investigated the neuroprotective effects of exercise training and/or diferuloyl methane (DM) supplement, which is known as curcumin, on lead acetate-induced neurotoxicity in the rat hippocampus. Sixty rats were randomly divided into six groups: 1) lead acetate, 2) DM supple...

abstract pollution is a world problem with serious consequences. heavy metals are an important group of these contaminants and enter aquatic ecosystems from anthropogenic and natural sources and animal health and systems are affected. in this study, the effect of lead exposure (3 mg/l concentration, 30 days) on activity of tissue enzymes, including acetyl cholinesterase, alanine aminotransferas...

Protective effect of Camellia Sinensis L. leaf extract on lead acetate Induced nephrotoxicity in albino wistar rats were investigated by analyzing various biochemical parameters. Lead acetate induced kidney damage was well manifested by significant increase in renal parameters like urea, uric acid creatinine and serum electrolytes sodium, potassium,chloride, calcium, phosphorous and TBARS and d...