In this issue of the Journal, Etzioni et al. (1) suggest a novel approach to estimating overdiagnosis in breast cancer. However, there is a key assumption in their method regarding the nature of overdiagnosis that is unlikely to hold and leads to an underestimate of the overdiagnosis rate. To understand this assumption, we need to go back to basic definitions. Lead time is the time from detecti...

Assuming a product space model for biometric and financial events, there exists a rather natural principle for the decomposition of gains of life insurance contracts into a financial and a biometric part using orthogonal projections. In a discrete time framework, the paper shows the connection between this decomposition, locally variance-optimal hedging and the so-called pooling of biometric ri...

The rising car usage deriving from growth in jobs and residential population results in air pollution, energy waste and unproductive and unpleasant consumption of people’s time. Public transport cannot be the only answer to this increasing transport demand. Car pooling has emerged to be a viable possibility for reducing private car usage in congested areas. Its actual practice requires a suitab...

As recent events have shown, simultaneous crop losses in different parts of the world can cause serious risks to global food security. However, to date, little is known about the spatial dependency of lower than expected crop yields from global breadbaskets. This especially applies in the case of extreme events, i.e., where one or more breadbaskets are experiencing far below average yields. Wit...

• A submitted manuscript is the author's version of the article upon submission and before peer-review. There can be important differences between the submitted version and the official published version of record. People interested in the research are advised to contact the author for the final version of the publication, or visit the DOI to the publisher's website. • The final author version ...

• A submitted manuscript is the author's version of the article upon submission and before peer-review. There can be important differences between the submitted version and the official published version of record. People interested in the research are advised to contact the author for the final version of the publication, or visit the DOI to the publisher's website. • The final author version ...