نتایج جستجو برای: leucine
تعداد نتایج: 22087 فیلتر نتایج به سال:
In the N-degron pathway of protein degradation Escherichia coli, N-recognin ClpS identifies substrates bearing N-terminal phenylalanine, tyrosine, tryptophan, or leucine and delivers them to caseinolytic protease (Clp). Chloroplasts contain Clp system, but whether chloroplastic ClpS1 adheres same constraints is unknown. Moreover, structural underpinnings substrate recognition are not completely...
This work aimed to develop a whole-cell biotransformation process for the production of α-ketoisocaproate from L-leucine. A recombinant Escherichia coli strain was constructed by expressing an L-amino acid deaminase from Proteus vulgaris. To enhance α-ketoisocaproate production, the reaction conditions were optimized as follows: whole-cell biocatalyst 0.8 g/L, leucine concentration 13.1 g/L, te...
An isotope dilution model for partitioning leucine uptake by the liver of the lactating dairy cow is constructed and solved in the steady state. If assumptions ae made, model solution permits calculation of the rate of leucine uptake from portal and hepatic arterial blood supply, leucine export into the hepatic vein, leucine oxidation and transamination, and synthesis and degradation of hepatic...
The specific radioactivity of free leucine has been measured in rat liver at various times after the injection of labeled leucine. The results of these measurements have served to calculate the effect of leucine reutilization on a previous measurement of the apparent turnover rate of catalase with labeled leucine as precursor. This effect was found to account entirely for the difference between...
Leucine, as an essential amino acid and activator of mTOR (mammalian target of rapamycin), promotes protein synthesis and suppresses protein catabolism. However, the effect of leucine on overall glucose and energy metabolism remains unclear, and whether leucine has beneficial effects as a long-term dietary supplement has not been examined. In the present study, we doubled dietary leucine intake...
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