Introduction: Gonadotropin-releasing hormone (GnRH) agonist triggers are increasingly used in antagonist vitro fertilization (IVF) cycles to prevent ovarian hyperstimulation syndrome (OHSS) following a robust response. The luteolytic effects of GnRH agonists inhibit implantation or spontaneous pregnancy, warranting freezing available blastocysts for future transfer after the risk OHSS subsides....

background: hormone therapy is currently the mainstay in the management of locally advanced and metastatic prostate cancer. we performed a systematic review to compare safety, efficacy and effectiveness of degarelix, a new gonadotropin-releasing hormone (gnrh) antagonist (blocker), versus gonadotropin-releasing hormone (gnrh) agonists. methods: medline, web of science and the cochrane library w...

Endometrial stromal sarcoma (ESS) formerly classified as low-grade endometrial stromal sarcoma is a rare uterine malignancy with a good prognosis despite a tendency to recur. Primary surgical management for ESS includes total abdominal hysterectomy and bilateral salpingo-oophorectomy. Patients with ESS have long disease-free survival rates when treated with primary surgical therapy, but nearly ...

Paraneoplastic syndrome associated with prostate cancer is extremely rare. We report a patient who presented with cholestatic jaundice without biliary duct obstruction, hepatic involvement, or infection. After a few detailed examinations, prostate cancer was diagnosed. After treatment with bicalutamide and leuprolide, the patient's symptoms and laboratory abnormalities were reversed. Cholestati...

A case of successful pregnancy in an in-vitro fertilization cycle, in spite of an accidental exposure to daily long-acting gonadotrophin-releasing hormone analogue administration, is reported. The patient underwent two intracytoplasmic sperm injection cycles with thawed epididymal spermatozoa, in which, due to a pharmacist's mistake, ovarian stimulation was carried out by a combination of long-...

This paper addresses the robust filtering problem for a class of linear genetic regulatory networks (GRNs) with stochastic disturbances, parameter uncertainties and time delays. The parameter uncertainties are assumed to reside in a polytopic region, the stochastic disturbance is state-dependent described by a scalar Brownian motion, and the time-varying delays enter into both the translation p...

In this paper we consider output-based stabilization of discrete-time LPV systems in the situation where the parameters are not exactly known, but only available with a finite accuracy. The controllers are obtained using a separate design of an observer and a state feedback and the interconnection is proven to stabilize the LPV system despite the mismatch between the true and available paramete...

The patient, a 45-year-old G3, P1-0-2-1 with a long history of uterine fibroids, was admitted to the defendant hospital center under the care of the defendant obstetrician/gynecologist on April 26 for a total abdominal hysterectomy (TAH) with bilateral salpingo-oophorectomy (BSO). The patient had been treated on and off by the defendant ob/gyn for over 5 years for left-sided fibroids and had tr...

Long-acting synthetic luteinising hormone-releasing hormone agonists have become the mainstay for androgen-deprivation therapy, because they avoid the physical and psychological discomfort associated with orchidectomy and lack the potential cardiotoxicity associated with estrogens such as diethylstilbestrol. Currently available luteinising hormone-releasing hormone agonist analogues include leu...

His past medical history was significant for an extensive left sided maxillary sinus surgery 27 years prior for a periorbital abscess complicating cellulitis and sinusitis; and Prostate cancer diagnosed 5 months prior to the current illness. He underwent radical prostatectomy; histopathology revealed Adenocarcinoma of the Prostate with positive surgical margins and Gleason score of 9. There was...