Lichen planus is a mucocutaneous disease that predominantly affects older patients and occurs much less frequently in the pediatric population. Furthermore, oral lichen planus is extremely rare in childhood with very few cases cited in the literature. The intention of this paper is to contribute two clinically and histologically documented cases of juvenile oral lichen planus cases to the liter...

The distribution of IgM and IgG in 20 cases of lichen planus and five cases of non-specific inflammation were studied by the unlabelled antibody-enzyme (PAP) technique. Routine paraffin sections were used. In lichen planus deposits of immunoglobulins were seen in and around epithelial cells, in colloid bodies, at epidermo-dermal junctions, and in some inflammatory cells. All cases examined for ...

Lichen planus is a rare inflammatory disease that affects the skin, mucous membranes, nails, and hair. It is characterized by shiny, polygonal, itching papules which vary in size and location. In the Anglo-American literature, the clinical characteristics of lichen planus are known by the four p's – purple, polygonal, pruritic, papules.The etiology and pathogenesis of disease are not well under...

BACKGROUND Oral lichen planus is a chronic inflammatory disease with a poorly understood etiology. The role of angiogenesis in the development of different chronic inflammatory diseases is of great concern. Vascular endothelial growth factor (VEGF) is an important regulator of angiogenesis. We aimed to evaluate the serum level of VEGF in patients with oral lichen planus compared with normal ind...

BACKGROUND AND AIMS The purpose of this study was to determine efficacy of 19% Elaeagnus angustifolia (EA) topical gel in the treatment of symptomatic oral lichen planus. MATERIALS AND METHODS Patients with symptomatic oral lichen planus referring to the Department of Oral Medicine, Fac-ulty of Dentistry at Shahid Beheshti University of Medical Sciences were asked to participate in the study....

in 1996 grinspan et al presented the association between primary hypertension and diabetes mellitus as grinspan syndrome. through various studies, researchers have noticed that epidermal lichen planus cells show enzymatic disorders as well as defective carbohydrate expression. therefore, it was assumed that there is a relationship between cells and hormones in metabolic actions. besides, some r...

BACKGROUND Lichen planus is recognized as an inflammatory disease of the skin with different morphologic patterns. Different treatment modalities, including topical and systemic corticosteroids, methotrexate, cyclosporine, azathioprine, topical calcineurin inhibitors, and psoralen plus UVA (PUVA), have been suggested for lichen planus. Although the efficacy of narrowband UVB (NBUVB) for treatme...

Actinic lichen planus (ALP) is a distinct variant of lichen planus mainly involving teenagers with an Asian racial profile. Three clinical types of ALP have been described: annular, pigmented, and dyschromic. We report an ALP with unusual presentation in a 56-year-old woman with no relevant medical history, which was clinically suggestive of actinic keratosis. Histological findings refined the ...

Lichen planus pemphigoides (LPP) is a rare blistering disease with features of both lichen planus and bullous pemphigoid. LPP typically appears on the extremities and occasionally involves the oral mucosa. Herein, we describe a case of LPP of the vulva of an 80-year-old woman, an uncommon location for this disease process. This clinical scenario can be confused with a number of similarly appear...

Background: Lichen planus has various clinical and epidemiologic features in different countries. Objectives: To determine clinical and epidemiologic patterns of lichen planus in dermatology department of Hamadan Sina Hospital during a ten-year period. Patients and Methods: This retrospective descriptive study was performed on 363 patients (Including 190 females and 173 males) suffered fr...