During ischemia, lidocaine or quinidine may prevent arrhythmias by blocking conduction without suppressing abnormal automaticity. The purpose of this study was to determine whether lidocaine or quinidine (5 Mg/ml) produced Purkinje fiber-papillary muscle block during superfusion in vitro with an altered Tyrode's solution containing some components of ischemia: 6 mM potassium, Po2 < 40, pH = 6.8...

PURPOSE To evaluate the effects of an intraperitoneal solution of methylene blue (MB), lidocaine and pentoxyphylline (PTX) on intestinal ischemic and reperfusion injury. METHODS Superior mesenteric artery was isolated and clamped in 36 adult male Sprague Dawley rats. After 60 minutes, clamp was removed and a group received intraperitoneally UNITO solution (PTX 25mg/kg + lidocaine 5mg/kg + MB ...

purpose: to compare the morphology and function of corneal enthothelial cell in early postoperative period after phacoemulsification with infusion or bolus intracameral adrenaline. methods: in this prospective randomized study, 71 eyes of 71 patients scheduled for phacoemulsification were randomly assigned to two groups: one group (31 eyes) received bolus intraocular adrenaline at 1/10,000 conc...

OBJECTIVES To test the efficacy of a new intravesical therapeutic solution in relieving urgency/frequency and pain in interstitial cystitis (IC). METHODS A solution of 40,000 U heparin, 8 mL 1% lidocaine (80 mg; group 1) or 2% lidocaine (160 mg; group 2), and 3 mL 8.4% sodium bicarbonate was administered intravesically in patients with newly diagnosed IC with significant frequency, urgency, a...

INTRODUCTION Incision and drainage of symptomatic emergency patients with facial swelling is painful even after local anesthetics are administered. The purpose of this prospective, randomized, double-blind study was to compare the pain of infiltration and the pain of an incision and drainage procedure of a buffered versus a nonbuffered 4% lidocaine formulation in symptomatic emergency patients ...

BACKGROUND AND OBJECTIVES Lidocaine concentration potentially able to determine nervous tissue injury is still not well established. This study aimed at investigating the effect of increasing spinal lidocaine concentrations in single injection through Quincke needle. METHODS After the Animal Experiment Ethical Committee approval, 40 adult animals were anesthetized with fentanyl and etomidate ...

A technique is described to reduce bleeding during operation for the correction of hare-lip and cleft-palate. The principle is to inject a vasoconstrictor solution around the arteries at their points of entry to the lip and palate. A total of not more than 2 ml is used of lignocaine 2 per cent combined with 1:80,000 adrenaline. A series of 125 operations was completed without adrenaline and the...

• Few tests compared local dental anesthesia with vasoconstrictor versus no vasoconstrictor. The vasoconstrictor seems to improve the effectiveness and the duration of the anesthesia. • Anesthetic associations containing 1/200,000 adrenaline concentration seem to present the most favourable balance benefit-risks. At this concentration, the quantities of adrenaline injected during everyday denta...