a validated hplc method was developed to determine doxorubicin concentration in a small volume of rat plasma (60 µl) with convenient fluorescence detection. sample preparation includes a simple one-step liquid-liquid extraction using minimum amount of organic solvent, with extraction recoveries more than 95%. the analysis was accomplished using perfectsil c18 column maintained at 35 °c and a mo...

Background:Extraction of drugs is one of the biggest concerns and the most important part of preparation and determination in forensic medicine. The lack of an easy, efficient and fast extraction method is the most important and most difficult problem despite the development of forensic centers and their being equipped with new diagnostic devices. In the present study, a comparison was conducte...

Extraction of trace amounts of toxic heavy metals from complicated environmental matrixes is a  challenging task. The aim of this investigation is the comparison of the extraction efficiencies and other related experimental variables ( chemicals, effect of pH, potential interfering ions) on the determination of inorganic lead ( ) which is present in waste water of dye industries. Compared techn...

Solid/liquid interfaces are important locations for various chemical reactions, such as electrode chemical reactions and metal corrosions. Conventional surface analytical methods, such as XPS and SEM-EDS, have been applied to solid materials after being removed from the liquid phase. These methods do not involve direct observation, although useful information is available. It is important to di...

in this study, porous scaffolds from poly(d,l-lactic acid) have been prepared via liquid- liquid phase separation method in ternary system of polymer-1,4-dioxane-water. polymer dissolved in dioxane in 1.5, 2.5 and 5 % wt/v and the solvent/non-solvent ratios were 13/87, 15/85 and 17/83. cloud point curves prepared by visual turbidometry. in order to obtain porous scaffolds with inter-connected p...

In the liquid liquid extraction (LLE) the extraction of rhodamine B (RB) from aqueous solutions by using 0.8M phenol in xylene was studied. The influencing parameters such as the effect of pH of the aqueous phase, the effect of extractant concentration, the effect of diluents and the stripping reagents has been investigated. The maximum extraction efficiency was obtained at pH 1±0.1 and the max...

The techniques of membrane extraction permit the application of classical liquid-liquid extraction (LLE) chemistry to instrumental and automated operation. Various shortcomings of LLE are overcome by membrane extraction techniques as they use none or very little organic solvents, high enrichment factors can be obtained and there are no problems with emulsions. A three phase SLM system (aq/org/a...

in this work, a procedure for preconcentration of silver using dispersive liquid–liquid microextraction with the reagent dithizone as complexing reagent was developed. at ph 2, silver ions are complexed with dithizone and extracted into the fine droplets formed when mixing carbon tetrachloride (extraction solvent), ethanol (disperser solvent) and the sample solution. after extraction, the phase...