Abstract Purpose The classic liquisolid technique is used to enhance the dissolution rate of poorly water-soluble drugs, but in some cases, it impossible reach desired using this alone. Therefore, a novel approach combination ball milling and technology was investigated improve for celecoxib. Methods First, celecoxib dispersed liquid vehicle (PEG 200), then ground mill 3 h. Other excipients, in...

Resveratrol is a class II drug in the Biopharmaceutics Classification System (BCS) with poor water solubility (0.03 mg/ml) and high permeability. Liquisolid system an innovative technique used for enhancing dissolution rate bioavailability of poorly soluble drugs. The present study demonstrated that loaded SNEDDS compacts were successfully developed. Ten formulation formulated different ratio o...