Alcoholic liver disease (ALD) spans a spectrum of liver pathology, including fatty liver, alcoholic steatohepatitis, and cirrhosis. Accumulating evidence suggests that dietary factors, including dietary fat, as well as alcohol, play critical roles in the pathogenesis of ALD. The protective effects of dietary saturated fat (SF) and deleterious effects of dietary unsaturated fat (USF) on alcohol-...

During the last years of the 20th century, diagnosis in liver pathology was enriched by additional methodologies including immunohistopathology and confocal microscopy. Nevertheless, it soon became obvious that ultrastructural examinations remain essential in both research and diagnosis. The present chapter focuses on the use of electron microscopy in diagnostic hepatology and research of unsol...

GOALS/BACKGROUND The aim of this study was to decipher whether end-stage liver failure modifies peripheral blood lymphocytes (PBL) in a homogeneous manner, independently of the base pathology, or, if on the contrary, PBL subsets show a different profile in each hepatic disease. METHODS We studied PBL subsets in 71 patients with end-stage liver disease, before liver transplant, and 74 healthy ...

UNLABELLED The AIM of this paper is to establish the values of liver stiffness (LS) assessed by means of ARFI in patients without known liver pathology and considered healthy subjects. MATERIAL AND METHOD the study group was composed of 82 subjects without known liver pathology, healthy volunteers or patients from other departments of our hospital who did not have altered liver laboratory tes...

Pyogenic liver abscess(PLA) which often presented by right sided abdominal pain and fever is a serious and life-threatening pathology. Biliary tract disease is the etiology of the abscess in most cases but sometimes the origin remains unidentified. A sigmoid septic source which maybe paucisymptomatic or hidden by an immunosuppressive treatment must be looked for. We present a case of liver absc...

The epithelial cell adhesion molecule (EpCAM) is highly expressed in the liver during development and diseases. However, its role pathology of remains to be explored. tissues EpCAM-/- wildtype (WT) mice at P0 stage were used for RNA sequencing. differently miRNAs, lncRNAs mRNAs selected confirmed by qPCR. expression metabolism-related gene SET domain bifurcated 2 (Setdb2) was significantly incr...