Unknown mechanisms exist to ensure that exons are not skipped during biogenesis of mRNA. Studies have connected transcription elongation with regulated alternative exon inclusion. To determine whether the relative rates of transcription elongation and spliceosome assembly might play a general role in enforcing constitutive exon inclusion, we measured exon skipping for a natural two-intron gene ...

Due to high computational complexity and quality degradation introduced by conventional frame-skipping transcoders, a DCT-based video frame-skipping transcoder is proposed recently. However, the transcoding process of the motion compensated macroblocks in the DCT domain becomes the bottleneck since IDCT and DCT processes are required. In this paper, we propose a new architecture of the frame-sk...

Duchenne muscular dystrophy (DMD) is a severe muscle-degenerative disease caused by a mutation in the dystrophin gene. Genetic correction of patient-derived induced pluripotent stem cells (iPSCs) by TALENs or CRISPR-Cas9 holds promise for DMD gene therapy; however, the safety of such nuclease treatment must be determined. Using a unique k-mer database, we systematically identified a unique targ...

TV logo detection, tracking and removal play an important role in the applications of claiming video content ownership, logo-based broadcasting surveillance, commercial skipping, and program rebroadcasting with new logos. In this paper, we present a novel and robust framework using tensor method for these three tasks. First, we use tensor based generalized gradient and the OTSU binarization alg...

Object-order texture-based volume rendering decomposes the volume data set into stacks of textured polygons. The performance of such hardwarebased volume rendering techniques is clearly dominated by the fill-rate and the memory bandwidth, while only very little workload is assigned to the vertex processor. In this paper we discuss a vertex program which efficiently computes the slicing for text...

We present an integrated approach for real-time performance prediction of volume raycasting that we employ for load balancing and sampling resolution tuning. In volume rendering, the usage of acceleration techniques such as empty space skipping and early ray termination, among others, can cause significant variations in rendering performance when users adjust the camera configuration or transfe...

This paper proposes a generic multi-dimensional scan shift control concept for multiple scan chain design. Multiple scan chain test scheme provides very low scan power by skipping (selectively load/unload) many long scan chain switching activities. Based on the two-dimensional scan shift control, we can achieve low test power with simple and small overhead structure. We can further extend the s...

This paper describes a system for retrieving relevant portions of complete broadcast news shows starting with only the audio data. A novel system of automatically detecting and removing commercials is described and shown to increase the performance of the system whilst also reducing the computational effort required. The sophisticated large vocabulary speech recogniser which produces the high-q...

Breakfast skipping is common in adolescents, but research on the effects of breakfast skipping on school performance is scarce. This current cross-sectional survey study of 605 adolescents aged 11–18 years investigatedwhether adolescents who habitually skip breakfast have lower endof-term grades than adolescents who eat breakfast daily. Additionally, the roles of sleep behavior, namely chronoty...

The first introns in eukaryotes are much longer than downstream introns. While the functional roles of large first introns have been studied extensively, investigations into the mechanisms leading up to extreme lengths are limited. Prominently, Hong et al. noted that the first introns are predominantly in 5’ UTR and suggested that its lengthening may have resulted from a 5’-ward shifting of don...