Breast cancer is the second most common malignancy in women. Common sites of metastases include the liver, lung, bone, and the brain. Metastases to the gastrointestinal tract are rare with patients presenting with small-bowel perforation, intestinal obstruction, and gastrointestinal bleeding. Here we report a case of a Saudi female presenting with invasive lobular carcinoma and ileo-cecal junct...

Background: Among the parameters that have a prognostic and/or predictive significance to therapeutic response, in case of breast carcinoma, study tumor-infiltrating lymphocytes carcinomas is emerging. The present aimed access clinicopathological profiles patients with primary carcinoma. Materials and Methods: Information was collected from archive Department Pathology, about invasive cancers d...

Breast cancer continues to be the most common tumor in women. Of these cases, 5 to 15% are composed of invasive lobular carcinoma (ILC), which has an increasing incidence in postmenopausal women (1). Borst et al. (2) compared the metastatic patterns of ILC versus infiltrating ductal carcinoma (IDC) and found that ILC is significantly more likely to metastasize to the gastrointestinal tract, gyn...

Gastrointestinal metastases from breast cancer are not common. We present a 58-year-old female diagnosed with lobular breast cancer some years before whose relapses were gastric and colonic mucosal. Simultaneous metastases are extremely rare. To our knowledge, no cases of initial dual affectation have been reported. The patient also showed gastritis by Helicobacter pylori. Invasive lobular brea...

INTRODUCTION Bilateral Breast Carcinoma (BBC) is a rare entity with incidence of synchronous carcinoma being 2-5% of all breast malignancies, which is much less than metachronous carcinoma. Synchronicity/ metachronicity are usually associated with local and lymphatic spread and with blood-borne spread to lungs, bones and liver. Moreover BBC are mostly lobular carcinomas but we report a rare cas...

The classical pattern of invasive lobular carcinoma (ILC) has become well established since the tumour was first designated in the 1940's. It is a distinct histological type of breast cancer, yet the incidence rates accumulated from the literature are widely divergent and vary from 0.7-20 per cent,' suggesting the criteria for diagnosis are not well defined. Martinez and Azzopardil in the only ...

Mutations in BRCA1 and BRCA2 increase a woman's lifetime risk of developing breast cancer by 43% to 84%. It was originally postulated that BRCA1/2-associated breast cancers develop more rapidly than sporadic cancers and may lack preinvasive lesions. More recent studies have found preinvasive lesions in prophylactic mastectomy specimens from mutation carriers; however, there is little informatio...

INTRODUCTION The use of conventional imaging techniques, namely mammography (MMG) and ultrasound (US), for breast cancer (BC) detection in women at high risk for the disease does not bring optimal results in many cases. AIM The present study evaluated the effectiveness of magnetic resonance (MR) mammography (MRM) in cases where US and MMG failed to detect suspected breast lesions. MATERIAL ...

Introduction: Breast cancer is one of the most common malignant tumors and leading causes related death amongst females worldwide. The clinical significance molecular classification carcinoma breast remains to be established. Molecular subtyping using immunohistochemistry can provide additional prognostic predictive information. Aim objectives: To identify morphological variants determine vario...