Description This package generates ranked lists of differential gene expression for either disease or drug profiles. Input data can be downloaded from Array Express or GEO, or from local CEL files. Ranked lists of differential expression and associated p-values are calculated using Limma. Enrichment scores (Subramanian et al. PNAS 2005) are calculated to a reference set of default drug or disea...

The current density of integration circuits, yields extremely complex Systems-on-a-Chip (SoCs) that take a long time to design and develop and thus, many times, they miss the market window for these products. This has motivated intensive research on High-level Synthesis (HLS) methodologies, so that such complex and custom systems are rapidly designed and prototyped. The contribution of this wor...

After the introduction of frame potentials by Benedetto and Fickus, there was an explosion of new results in frame theory. The generalization of this notation to weighted frame potentials yields a physical interpretation for finite frames along the lines of Coulomb’s law in physics. This allows us to use results from classical mechanics to anticipate new results in frame theory. All of this res...

The Teramac configurable hardware system can execute synchronous logic designs of up to one million gates at rates up to l megahertz. A fully configured Teramac includes half a gigabyte of RAM and hardware support for large multiported register files. The system has been built from custom FPGA's packaged in large multichip modules (MCMs). A large custom circuit (-1,000,000 gates) may be compile...

Radio frequency identification (RFID), The real-time location of objects and ability to track motion provide a wide range of useful applications in areas such as safety, security and supply chain. In recent years, radio frequency identification technology has moved from obscurity into mainstream applications that help speed the handling of manufactured goods and materials. RFID enables identifi...

Dental implants with their increasing success rates and predictability of final outcome are fast becoming the treatment of choice for replacing missing teeth. Considering the success of immediate implant placement in reducing tissue loss and achieving good esthetic results, is making it a more popular treatment modality in implant dentistry. Understanding the management of gingival tissues in r...

The design challenges and custom design techniques associated with low-power, smallarea, high-performance CMOS digital signalprocessing circuits for hard-disk-drive applications are presented. The advantages of custom design are demonstrated by an example custom digital FIR filter macro that provides substantial improvement in performance, area, and power dissipation over standard-cell implemen...

For CMOS feature size of 65 nm and below, local (or intra-die or within-die) variations in transistor Vt contribute stochastic variation in logic delay that is a large percentage of the nominal delay. Moreover, when circuits are operated at low voltage (Vdd ≤ 0.5V), the standard deviation of gate delay becomes comparable to nominal delay, and the Probability Density Function (PDF) of the gate d...