Jim Smith is Director of Science at the Wellcome Trust and a group leader at the Francis Crick Institute, where he was formerly Director of Research. A Fellow of both the Royal Society and the Academy of Medical Sciences, he was knighted for his services to medical research and science education in 2016. His lab works on mesoderm induction in the early vertebrate embryo. We met Jim in the Crick...

tutes unsoundness of mind. To constitute a " lucid interval," the party must freely and voluntarily, and without the design of pretending sanity, confess his delusion. After making a few preliminary observations, Lord Brougham observes? " The principles which must govern a case of this description are sufficiently clear, and they may be regarded as well settled by the current of former decision...

Pain is a word every human being can understand. Except those with congenital insensitivity to pain there is probably no human being that has completely escaped the perception of pain. Pain is an unpleasant feeling related to a physical aggression compromising the integrity of the body. It also has an emotional component that may be weak or strong. The fear of pain may be as disturbing as pain ...

Tub late Governor of Madras is reported to have spoken as follows in tlie public health section of the Social Science Association :?" While 1 was in India there were about eight thousand prisoners in the Presidency of Madras, and a plan being laid down for tlie improvement of the jail accommodation, it became my duty to prosecute that plan with all the energy and vigour I could. We commenced by...