BACKGROUND Although mass screening for osteoporosis is not recommended among postmenopausal women, there is no consensus on which women should undergo testing for low bone mineral density. The objective of this study was to develop and validate a clinical tool to help clinicians identify which women are at increased risk for osteoporosis and should therefore undergo further testing with bone de...

OBJECTIVE Because small increments in levels of endogenous plasma estradiol are associated with higher postmenopausal bone mineral density, we investigated the safety and effectiveness in preventing bone loss of unopposed, very-low-dose transdermal estradiol for postmenopausal women. METHODS This was a randomized, placebo-controlled, double-blind trial with 2-year follow-up at 9 United States...

Background: Failure to maintain bone mass density is a major complication in patients with cystic fibrosis (CF). This study was conducted to evaluate the prevalence of low bone mineral density (BMD) and also identifying associated risk factors in CF patients. Materials and Methods: Present study conducted on 59 CF patients aged 5-35 years referred to respiratory clinic of Masih Daneshvari Hospi...

diabetes mellitus (dm) and osteoporosis are common diseases and their prevalence increases with age. several investigations have indicated that type 1 dm has a significant relationship with bone loss, whereas in type 2 diabetes, this relationship is controversial. therefore, this study was conducted to determine the relationship between osteoporosis and type 2 dm in elderly people. this populat...

background: low bone mass is a frequent complication of chronic inflammatory disease. the pathogenesis of osteoporosis in chronic inflammatory disease may be secondary to releases of cytokines such as tnf-a and il6. chronic gastritis due to helicobacter pylori (hp) infection may lead to decreased bone mineral density (bmd) and predispose patients to osteoporosis. the objective of this study was...

objective: osteoporosis is the most common metabolic disease of the bone decreasing bone mineral density (bmd) particularly in postmenopausal women. on the other hand, panoramic radiography has several applications in dentistry. it appears that by calculating some indices on panoramic radiographs, we may be able to predict the risk of osteoporosis in high-risk individuals. the present study was...

introduction: osteoporosis is a bone disease in which there is a reduction in the amount of bone mineral content leading to an increase in the risk of bone fractures. the affected individuals not only have to go through lots of pain and suffering but this disease also results in high economic costs to the society due to a large number of fractures.  a timely and accurate diagnosis of this disea...

introduction:there is considerable amount of controversy about the long term effects of multiparity and duration of breast-feeding on maternal bone mineral density after menopause. this study was conducted to determine whether multiple pregnancy and prolonged duration of breast-feeding are independent predictors of low bone mass in post-menopausal kurdish women. methods: in a retrospective stud...

OBJECTIVE To assess the value of monitoring response to bisphosphonate treatment by means of measuring bone mineral density. DESIGN Secondary analysis of trial data using mixed models. Data source The Fracture Intervention Trial, a randomised controlled trial that compared the effects of alendronate and placebo in 6459 postmenopausal women with low bone mineral density recruited between May 1...

Inhaled glucocorticosteroids are clearly beneficial in subjects with moderate or severe asthma since they are well tolerated, reduce symptoms, and improve quality of life. Some studies suggest that inhaled glucocorticosteroids can adversely affect bone mineral density. The aim of this study is to determine the effects of inhaled glucocorticosteroid therapy on bone mineral density in female pati...