The aim of the present study was to investigate mechanism of the gender differences of B cells. The results showed that 358 differential gene expressions (DEGs) were displayed between healthy females and males. Compared with male, 226 and 132 genes were found to be up- and downregulated in the female. 116 genes displayed possible correlation with estrogen. Moreover, the upregulated DEGs (Cav1, ...

Repetitive hypoxia followed by persistently increased ventilatory motor output is referred to as long-term facilitation (LTF). LTF is activated during sleep after repetitive hypoxia in snorers. We hypothesized that LTF is activated in obstructive sleep apnea (OSA) patients. Eleven subjects with OSA (apnea/hypopnea index = 43.6 +/- 18.7/h) were included. Every subject had a baseline polysomnogra...

Macrophages are multifunctional cells that perform diverse roles in health and disease and considered the main source of inflammatory cytokines in affected joints of patients with rheumatoid arthritis (RA). M2 macrophages are well known as anti-inflammation and wound-healing cells; however, recent evidence suggests that they can also promote inflammation in RA, although the underlying mechanism...

The time course of the requirement for local protein synthesis in the stabilization of learning-related synaptic growth and the persistence of long-term memory was examined using Aplysia bifurcated sensory neuron-motor neuron cultures. We find that, following repeated pulses of serotonin (5-HT), the local perfusion of emetine, an inhibitor of protein synthesis, or a TAT-AS oligonucleotide direc...

Withdrawal reflexes of the mollusc Aplysia exhibit sensitization, a simple form of long-term memory (LTM). Sensitization is due, in part, to long-term facilitation (LTF) of sensorimotor neuron synapses. LTF is induced by the modulatory actions of serotonin (5-HT). Pettigrew et al. (1) developed a computational model of the nonlinear intracellular signaling and gene network that underlies the in...

Abstract Providing effective and sustainable water disinfection methods, without harmful by-products, is essential to protect public health safety. It hypothesized that the application of liquid-thin-film (LTF) technology can enhance bactericidal activity both ultraviolet (UV) irradiation ozone (O3) treatments. Therefore, this study aimed examine synergistic effect combined UV + O3 LTF treatmen...

This report presents solutions of EUNITE Competition 2003 problem “Prediction of product quality in glass manufacturing process”. The first solution is based on Local Transfer Function Approximator (LTF-A) neural network, while the next three solutions utilize simple rules to predict glass quality. Despite advanced data preprocessing, LTF-A did not performed very well on the competition data. T...

Adipocyte tissue inflammation orchestrates the occurrence and development of diseases induced by obesity. Here, effects Lagerstroemia speciosa (L.) Pers total flavonoids (LTF) on TNF-α-induced insulin resistance (IR) inflammatory response in 3T3-L1 adipocytes underlying mechanisms were studied. Cell glucose uptake test confirmed that TNF-α could induce IR adipocytes. The sensitivity to was incr...

The effect of applied voltage V on local thickness fluctuations (LTF) in lipid bilayers is examined using the continuum model and accounting for non-locality of membrane elastic moduli. Ponderomotive forces, calculated from the linearized Poisson-Boltzmann equation, reduce LTF energy quadratically with V . Combined with a significant increase in the apex field gradient and perturbation of lipid...