Case: An 18-month-old male infant originally presented with swelling in the right neck near the angle of the jaw which gradually developed over 4 to 5 days. He was fi rst taken to his primary care provider who noted multiple enlarged, nontender, submandibular lymph nodes and prescribed amoxicillin. However, because of increasing swelling after several days of antibiotic use, the patient was tak...

Tuberculosis (TB) is responsible for a high burden of disease and estimated to affect one third of the world population with most in developing countries [1]. Extra pulmonary TB accounts for about 7-30% of TB cases and lymphadenitis accounts for 17-43% of cases. Cervical lymph nodes constitute the most common site of involvement with axillary nodes affected in 3.8-20.3% of tuberculous lymphaden...

BACKGROUND The diagnostic values of interferon-gamma release assays (IGRA) in tuberculosis (TB) vary a lot with different site of infections, with especially higher sensitivities in chronic forms of TB such as tuberculosis of the lymph node. We conducted a meta-analysis to comprehensively evaluate the overall accuracy of diagnostic IGRA for tuberculous lymphadenitis. METHODS Pubmed, Web of Sc...

Kikuchi–Fujimoto disease (KFD), also known as histiocytic necrotizing lymphadenitis, is a rare and generally self-limiting of uncertain etiology that presents with fever cervical lymphadenopathy in both the pediatric adult populations. Here, we present case 5-year-old male who presented acute onset which was initially diagnosed managed staphylococcal lymphadenitis. He underwent an excisional bi...

Rifampin, isoniazid, and ethambutol were administered in single daily dose for nine months to 91 patients with pleural effusion and 45 patients with lymphadenitis, both of tuberculous etiology. Clinical and roentgenographic clearance of pleural effusion was successfully achieved in all cases at the end of nine months of treatment. Followup of 80 cases of pleural effusion up to nine months, in 5...

Histiocytic necrotizing lymphadenitis, or Kikuchi's lymphadenitis (KL), is an unusual form of lymphadenitis, generally with self-limited clinical course. KL has been reported in rare patients infected with the human immunodeficiency virus (HIV). Pathogenesis of the lesion is probably related to an impaired immune function. The purpose of the present article is to report on one case in which KL ...

Clinical course of acute nonspecific lymphadenitis of the face and neck is studied in 241 patients aged 1-14 years in order to improve the diagnosis and therapy of this condition. General clinical examinations were supplemented by laser biophotometry and assessment of the activities of some local defense factors (lysozyme, beta-lysine, secretory and serum IgA). Multiple-modality treatment for t...

Tuberculosis lymphadenitis (TBLN) is the most common extra pulmonary TB (EPTB) case in world with a range of 30-40% all EPTB cases. When body's immune system cannot kill pathogen, body will try to contain pathogen (granuloma). The outer portion granuloma becomes calcified and cells center undergo necrosis. formation central necrosis associated emergence cellular hypersensitivity features local ...

BACKGROUND & OBJECTIVES The emergence of drug resistance tuberculosis (TB) is a significant challenge for TB control and prevention programmes, and the major problem is multidrug resistant tuberculosis (MDR-TB). The present study was carried out to determine the frequency of drug resistant Mycobacterium tuberculosis isolates among newly and retreated TB lymphadenitis patients and risk factors f...

Background: Only 17 cases of neonatal submandibular sialadenitis have been described in neonates. These infections are frequently caused by gram-positive cocci. We unexpectedly observed multiple cases of sialadenitis and cervical adenitis in our regional NICU within a few years, as staphylococcal aureus infections have become more prevalent in the hospital and community. Therefore, we postulate...