ferulago w. koch. (apiaceae) genus is represented by approximately 50 taxa throughout the world. ferulago species are known as “çakşır” or “çağşır” in turkey and mostly known for their aphrodisiac effects. however recent reports emphasize the activity of various ferulago species against cancer, as well. the aim of this study was to investigate the effect of lyophilized extract of f. mughlea peş...

The polyelectrolytes poly(L-lysine) (PLL, Mw = 2.60 × 10 Da) and hyaluronic acid (HA, Mw = 1.32 × 10 Da) were purchased from Sigma Aldrich (Saint-Quentin Fallavier, France) and Lifecore Biomedical (Chaska, USA) respectively. Coupling agents as N,N′Dicyclohexylcarbodiimide 99% (DCC), N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride ≥ 98% (EDC), N-Hydroxysuccinimide 98% (NHS), and NHy...

The development of tumor-selective radiopharmaceuticals is clinically desirable as a means of detecting or confirming the presence and location of primary and metastatic lesions and monitoring tumor response to (chemo)therapy. In addition, the application of targeted radiotherapeutics provides a unique and effective modality for direct tumor treatment. In this manner the radioimmunotherapy (RIT...

BACKGROUND In recent years there have been considerable interests in the use of probiotic live cells for nutritional and therapeutic purposes. This strategy can be concomitant with some limitations such as survival of live cell during the GI-transit and their effective delivery to target tissues upon ingestion. Several attempts have been made to overcome these limitations such as their microenc...

An automated, computerized system, the AutoMicrobic System, has been developed for the detection, enumeration, and identification of bacteria and yeasts in clinical specimens. The biological basis for the system resides in lyophilized, highly selective and specific media enclosed in wells of a disposable plastic cuvette; introduction of a suitable specimen rehydrates and inoculates the media in...

Dengue virus (DENV) infection causes sudden fever along with several nonspecific signs and symptoms and in severe cases, death. DENV is transmitted to people by Aedes aegypti and Ae. albopictus mosquitoes, whose populations increase during rainy season. West Nile Virus (WNV), Rickettsia spp. and Leptospira spp. are fever-causing pathogens that share many of the initial symptoms of DENV infectio...

Staphylococcus aureus phage ISP was lyophilized, using an Amsco-Finn Aqua GT4 freeze dryer, in the presence of six different stabilizers at different concentrations. Stability of the lyophilized phage at 4 °C was monitored up to 37 months and compared to stability in Luria Bertani broth and physiological saline at 4 °C. Sucrose and trehalose were shown to be the best stabilizing additives, caus...

Experience in the management of 77 isolated orbital floor fractures is presented. The transconjunctival approach was used exclusively to access the orbital floor and lyophilized dura and cartilage were used to reconstruct the floor, when indicated. Follow-up for an average of 36 months showed excellent cosmetic and functional results. A 20% complication rate was noted, which compares favorably ...