We consider BF-type topological field theory coupled to non-dynamical particle and string sources on spacetime manifolds of the form IR1 × M3, where M3 is a 3-manifold without boundary. Canonical quantization of the theory is carried out in the Hamiltonian formalism and explicit solutions of the Schrödinger equation are obtained. We show that the Hilbert space is finite dimensional and the phys...

M3 reflection intensity (I(M3)) from tetanized, intact skeletal muscle fiber bundles was measured during sinusoidal length oscillations at 2.8 kHz, a frequency at which the myosin motor's power stroke is greatly reduced. I(M3) signals were approximately sinusoidal, but showed a "double peak" distortion previously observed only at lower oscillation frequencies. A tilting lever arm model simulate...

In this letter we demonstrate the genericity of suppressed gaugino masses Ma ∼ m3/2 ln(MPlanck/m3/2) in the IIB string landscape, by showing that this relation holds for D7-brane gauginos whenever the associated modulus is stabilised by nonperturbative effects. Although m3/2 and Ma take many different values across the landscape, the above small mass hierarchy is maintained. We show that it is ...

We developed a new laboratory polymerizing unit (Twinkle MIII: M3) equipped with different light sources (a metal halide and two halogen lamps) that could illuminate independently. This study introduced the structure of the curing unit and examined the curing depth of a representative indirect composite (Artglass). The composite material was cured with the following modes: 1) M3 - halogen only;...

Trophic interactions of introduced biocontrol fungi with soil animals can bea key determinant in the fungal proliferation and activity.This study investigated trophic interaction of an introduced biocontrol fungus with soil nematodes. The biocontrol fungusTrichoderma harzianum ThzID1-M3 and the fungivorous nematode Aphelenchoides sp. (10 per gram of soil) were added to nonsterile soil, and micr...

The in vitro metabolism of buprenorphine was investigated to explore new metabolic pathways and identify the cytochromes P450 (P450s) responsible for the formation of these metabolites. The resulting metabolites were identified by liquid chromatography-electrospray ionization-tandem mass spectrometry. In addition to norbuprenorphine, two hydroxylated buprenorphine (M1 and M2) and three hydroxyl...

Cholinergic agents elicit prominent smooth muscle contractions via stimulation of muscarinic receptors that comprise five distinct subtypes (M1-M5). Although such contractions are important for autonomic organs, the role of each subtype has not been characterized precisely because of the poor selectivity of the currently available muscarinic ligands. Here, we generated a mutant mouse line (M2-/...

Ambient monitoring of acid aerosols in four U.S. cities and in a rural region of southern Ontario clearly show distinct periods of strong acidity. Measurements made in Kingston, TN, and Steubenville, OH, resulted in 24-hr H+ ion concentrations exceeding 100 nmole/m3 more than 10 times during summer months. Periods of elevated acidic aerosols occur less frequently in winter months. The H+ determ...

The olfactory system in rodents serves a critical function in social, reproductive and survival behaviours. Processing of chemosensory signals in the brain is dynamically regulated in part by an animal's physiological state. We previously reported that type 3 muscarinic acetylcholine receptors (M3-Rs) physically interact with odorant receptors (ORs) to promote odour-induced responses in a heter...

Volume analysis of purified human blood monocytes revealed distinct populations of large and small cells. Computer curve fitting suggested a third, intermediate-sized population. These monocytes were designated M1, M2, and M3 in order of increasing size, and their approximate volumes were 150, 250, and 480 micron3, respectively. The three subpopulations were present in all 30 normal individuals...