نتایج جستجو برای: macular degeneration
تعداد نتایج: 73965 فیلتر نتایج به سال:
Reduced foveal cone optical density in diseased eyes with normal acuity can affect color matches. Using field diameters of 1 degree, 2 degrees, 4 degrees, and 8 degrees, we measured mean color-match midpoints and match widths in patients who had good acuity and who exhibited three categories of eye disease: hereditary macular degeneration (n = 12), retinitis pigmentosa (n = 19), and glaucoma (n...
Treatment of retinal diseases such as age-related macular degeneration (AMD), macular edema and occlusive vascular disease has benefitted greatly from basic and translational research. Understanding of the role of vascular endothelial growth factor (VEGF) led to the development of its inhibitors, which are now widely applied. 1 In this issue of JOVR, Nourinia et al 2 investigate a potentially n...
PREVENT DIABETES AMD is an acronym for “Age Related Macular Degeneration”. It is a disease where the retina degenerates, destroying central vision, leaving only peripheral vision. It is the leading cause of blindness in people over 55 years of age, affecting between 25 and 30 million people worldwide. In the journal Ophthalmology (February 2008, Volume 115, Issue 2, Pages 324-333) found Macular...
Citation: Yu SS, Tang X, Ho Y-S, Chang RC-C and Chiu K (2016) Links between the Brain and Retina: The Effects of Cigarette Smoking-Induced Age-Related Changes in Alzheimer’s Disease and Macular Degeneration. Front. Neurol. 7:119. doi: 10.3389/fneur.2016.00119 Links between the Brain and Retina: The Effects of Cigarette Smoking-induced Age-Related Changes in Alzheimer’s Disease and Macular Degen...
BACKGROUND AND OBJECTIVE The purpose of this study is to compare cancellation and no-show rates in patients with diabetic macular edema (DME) and exudative macular degeneration (wet AMD). PATIENTS AND METHODS An anonymous survey was sent to 1,726 retina specialists inquiring as to the number of appointments their patients with DME and wet AMD attended, cancelled, or did not show up for in 201...
Treacher Collins syndrome (TCS) results from defects in a nucleolar trafficking protein (Treacle) coded for by the TCOF1 gene. The purpose of this report is, firstly, to describe an isolated male with TCS associated with macular degeneration who also had a novel TCOF1 gene mutation and, secondly, to evaluate this mutation in a well characterised cohort of 95 patients with age related macular de...
Familial macular degeneration is a clinically and genetically heterogeneous group of disorders characterized by progressive central vision loss. Here we show that an R373C missense mutation in the prominin 1 gene (PROM1) causes 3 forms of autosomal-dominant macular degeneration. In transgenic mice expressing R373C mutant human PROM1, both mutant and endogenous PROM1 were found throughout the la...
Objective. To estimate the net health benefits of pegaptanib and ranibizumab by considering the impact of visual acuity and unintended effects (cardiovascular and hemorrhagic events) on quality-of-life among persons with neovascular age-related macular degeneration. Methods. We designed a probabilistic decision-analytic model using published data. It employed 17 visual health states and three f...
Macular degeneration is one of the most common retinal diseases in India. Usually it is observed in people over 60s and is therefore called age related Macular degeneration, ARMD or AMD. The macula is responsible for the sharp central vision needed for detailed activities such as reading, writing, driving, face recognition and ability to see colours. Age related macula degeneration is degenerat...
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