AIM The study was a prospective randomised controlled double-masked trial performed in two centres to compare sub-threshold micropulse diode laser photocoagulation (MPDL) with conventional green laser photocoagulation (CGL) in the treatment of clinically significant diabetic macular oedema (CSMO). METHODS Fifty-three patients (84 eyes) with diabetic CSMO were randomly assigned to MPDL (n = 44...

Aims: To determine the eligibility for laser photocoagulation treatment or for photodynamic therapy (PDT) with verteporfin in eyes at the earliest stage (first month of symptoms) of exudative age related macular degeneration (AMD) based on fluorescein angiographic (FA) features; to evaluate the potential contribution of indocyanine green angiography (ICG-A) for occult choroidal neovascularisati...

Panretinal Photocoagulation (PRP) has been approved as an effective treatment for stopping retinal neovascularization in patients with severe diabetic retinopathy [1-3]. This treatment constitutes performing multiple laser photocoagulation sessions on the peripheral retina with the purpose of destroying photoreceptor and retinal pigment epithelium cells under the treated retina. While PRP damag...

PURPOSE To compare modified Early Treatment Diabetic Retinopathy Study (mETDRS) focal/grid laser photocoagulation with normal-density (ND-SDM) or high-density (HD-SDM) subthreshold diode-laser micropulse photocoagulation for the treatment diabetic macular edema (DME). METHODS A prospective, randomized, controlled, double-masked clinical trial with patients with previously untreated DME and be...

BACKGROUND The purpose of this study was to compare the safety and efficacy of combined vitrectomy, intravitreal triamcinolone acetonide (IVTA), and bevacizumab injection with that of IVTA and bevacizumab injection and subsequent macular grid laser photocoagulation for the treatment of intractable diffuse diabetic macular edema. METHODS This randomized controlled clinical trial was performed ...

OBJECTIVE To investigate the predictive baseline factors for a successful outcome following one dose of intravitreal triamcinolone acetonide (IVTA) in patients with macular oedema (ME) caused by branch retinal vein occlusion (BRVO). METHODS This retrospective study enrolled patients with ME (macular retinal thickness [MRT] ≥ 300 µm) due to BRVO who still had ME 3 months after grid laser photo...

Diabetic cystoid macular oedema (DME) is a common cause of visual acuity (VA) decrease. Good anatomical results and VA of pars plana vitrectomy (PPV) in cases of macular hole internal limiting membrane (ILM) peeling leads to usage of this technique in DME. A favorable result even in a case without vitreoretinal traction leads to conclusion that pathogenesis of this disease is different. We anal...

PURPOSE The authors studied the efficacy of intravitreal triamcinolone acetonide in a case series of patients with diffuse diabetic macular edema without evidence of vitreous-macular traction refractory to laser photocoagulation. METHODS Six eyes with clinically diffuse diabetic macular edema that failed to respond to at least two previous sessions of laser photocoagulation were included. The...

PURPOSE The purpose of this study was to evaluate and compare microperimetry and fundus autofluorescence (FAF) after subthreshold micropulse diode laser versus modified Early Treatment Diabetic Retinopathy Study photocoagulation for clinically significant diabetic macular edema. METHODS A prospective randomized clinical trial including 62 eyes (50 patients) with untreated, center-involving, c...

PURPOSE The purpose of this study was to determine whether eyes with center-involved diabetic macular edema, treated with focal/grid photocoagulation, in which there is a reduction in central subfield thickness (CST) measured with optical coherence tomography after 16 weeks, will continue to improve if retreatment is deferred. METHODS This is a prospective, multicenter, observational, single-...