Single-agent dynamic optimization models. In these lecture notes we consider specification and estimation of dynamic optimization models. Focus on single-agent models. • Rust (1987) is one of the first papers in this literature. Model is quite simple, but empirical framework introduced in this paper for dynamic discrete-choice (DDC) models is still widely applied. • Agent is Harold Zurcher, man...

Gastric cancer is still one of the cancers with highest mortality. Most patients present with advanced-stage disease. Palliative chemotherapy is usually the only treatment option for patients with advanced gastric cancer (AGC). Maintenance chemotherapy is an evolving concept in medical oncology. Maintenance chemotherapy can be administered with the same drug(s) in the initial regimen or with an...

A generic broker agent architecture is introduced, designed in a principled manner using the compositional development method for multi-agent systems DESIRE. A flexible, easily adaptable agent architecture results in which, in addition, facilities have been integrated that provide automated support of the agents own maintenance. Therefore, the agent is not only easily adaptable, but it shows ad...

The Virtual Secretary (ViSe) is a kind of intelligent agent that could assist its user in major secretarial work. Users give the orders of what to do, while agents figure out how to do and carry out the tasks. This paper presents the ViSe agents in two aspects: (1) construct individual agent on three intelligence levels: knowledge-base level, learning level and cooperation level; and (2) to mod...

The Virtual Secretary (ViSe) is a kind of intelligent agent that could assist its user in major secretarial work. Users give the orders of what to do, while agents gure out how to do and carry out the tasks. This paper presents the ViSe agents in two aspects: (1) to construct individual agent on three intelligence levels: knowledge-base level, learning level and cooperation level; and (2) to mo...

This study shows the usefulness of Artificial Neural Network (ANN) in maintenance planning and man-agement. An ANN model based on the multi-layer perceptron having three hidden layers and four processing elements per layer was built to predict the expected downtime resulting from a breakdown or a maintenance activity. The model achieved an accuracy of over 70% in predicting the expected downtime.

A rational agent derives its choice of action from its beliefs and goals. Goals can be distinguished into achievement goals and maintenance goals. The aim of this paper is to define a mechanism which ensures the satisfaction of maintenance goals. We argue that such a mechanism requires the agent to look ahead, in order to make sure that the execution of actions does not lead to a violation of a...

As functional (total care) products emerge in the jet engine industry, the need for product life-cycle models capable of definition and evaluation of life cycle properties increases, since functional products (FP) includes both hardware and service. Recent life-cycle models are intended for hardware products and mostly handle design and manufacturing knowledge. The aim of this article is to pre...

As functional (total care) products emerge in the jet engine industry, the need for product life-cycle models capable of definition and evaluation of life cycle properties increases, since functional products (FP) includes both hardware and service. Recent life-cycle models are intended for hardware products and mostly handle design and manufacturing knowledge. The aim of this article is to pre...