Background: Beta-thalassemia is an autosomal recessive hemoglobinopathy with frequent skeletal complications, often debilitating in adolescent patients. We aim to evaluate the bone mineral density (BMD) by dual-energy x-ray absorptiometry (DEXA) and ascertain osteoporosis/osteopenia frequency patients β-thalassemia major. Methodology:  In this cross-sectional study, 36 major were enrolled from...

Background: β-thalassemia is rare in sub-Saharan Africa and to our knowledge there has been no case of homozygous major reported from this region. In a recent cohort study, we identified four mutations among 83 heterozygous carriers Kilifi, Kenya. One the was β-globin gene initiation codon mutation (ATG➝ACG) (rs33941849). Here present patient with resulting mutation,...