Introduction: Self-care is the core concept of health care and may be considered as one's stabilization, and restoration as well as the improvement of his/her health and well-being. Looking at the process of Self-care from patients' perspective who suffer from thalassemia may assist the nurses and health care providers to facilitate the health process. Thus this study was conducted to discover ...

background: beta-thalassemia major is one of the major health problems in our country. many studies have confirmed the fact that, these patients have an increased susceptibility to bacterial infections. objective: in this study, we have assessed the humoral immune system in 68 thalassemic patients by measuring their serum concentration of immunoglobulin g (igg), igm, iga, c3 and c4 in order to ...

Despite recent advances in iron chelation therapy, excess iron deposition in pituitary gonadotropic cells remains one of the major problems in thalassemic patients. Hypogonadism, mostly hypogonadotropic hypogonadism, is usually detected during puberty. Early diagnosis and treatment are crucial for normal pubertal development and to reduce the complications of hypogonadism. The risks and benefit...

Serum concentrations of T4, T3, rT3, and TSH were measured by radioimmunoassay in 45 patients suffering from beta-thalassaemia. A TRH stimulation test was performed and the binding capacity of TBG and TBPA for T3 and T4 measured by reverse flow zone electrophoresis in a group of these patients. Mean T4 serum concentration was lower in thalassaemic patients than controls; T3, rT3, TSH levels, an...

Objective: The purpose of the study was to examine the blood lipid profile in children with beta-Thalassemia major, and to determine the factors that affect it. Material and Method: Files of eighty-five patients between the ages of five and fifteen with beta-Thalassemia major who were receiving regular chelation therapy followed by from paediatric policlinic of our hospital were examined retros...

background: transfusion is the mainstay treatment of patients with thalassemia major and occasionally in thalassemia intermediate. alloimmunization is an unwanted side effect of blood transfusion. the present study intended to determine the frequency of alloimmunization in patients with β- thalassemia major and thalassemia intermediate in southwest iran. patients and methods: this was a cross-s...

a, fi, and ‘i globin chain synthesis in bone marrow and peripheral blood reticulocytes were studied in two patients with thalassemia major, two with thalassemia intermedia, one with thaIassemia minor, one with Hb H disease, and one with homozygous f38-thalassemia. Nine nonthalassemic patients served as controls. In thalassemia major, a marked imbalance of ato fichain synthesis was found in the ...

BACKGROUND Thalassemia is a heterogeneous disorder and several genetic factors influence the severity of thalassemia. An accurate and early diagnosis of a mild thalassemia genotype helps to avoid unnecessary transfusion and its complications. The aim of this study is to identify the association between XmnI polymorphism and disease severity in patients with beta-thalassemia from northern Pakist...

AIM The aim of this report is to present the management of the maxillary deformity and subsequent implant therapy of a case with β-thalassemia major. BACKGROUND β-thalassemia is a hematologic disorder that results from the abnormality of the β-globulin chain synthesis. The best known thalassemia-induced dentofacial problem is the maxillary enlargement, and this undesirable growth of maxilla a...

To estimate the levels of folic acid, vitamin B12 and their relationship with ferritin in βthalassemia major children. Thirty children with β-thalassemia major in the age group of 4 to 8 years were studied for estimation of serum ferritin, folic acid and vitamin B12 over a period of one year. These tests were determined by means of Immulite 1000 analyzer. The statistical analysis of β-thalassem...