BACKGROUND Thrombocytopenia is often seen in the patients of malaria infected with Plasmodium vivax. We studied patients admitted in hospital having coexisting thrombocytopenia and malaria, and recorded the response to anti-malarial therapy. METHODS In this cross-sectional descriptive study, a total of 120 patients admitted in medical ward with Plasmodium vivax malaria and co-existing thrombo...

the examination of the blood, the taking of specimens of blood, the staining and microscopic examination of the blood and the great necessity of being acquainted with thtf appearance of normal blood. The three species of parasite, other' blood parasites, the method of collecting sample of blood for serum diagnosis, the examination of sputum, etc. These subjects are rightly included in this book...

Artemisinins are a family of sesquiterpene trioxane lactone anti-malarial agents originally derived from Artemisia annua L. The anti-malarial action of artemisinins involves the formation of free radicals via cleavage of the endoperoxide bond in its structure, which mediate eradication of the Plasmodium species. With its established safety record in millions of malarial patients, artemisinins a...

was a clear association with malaria, and that all these four cases responded well to treatment with quinine, whereas the other two patients were discharged with evidence of permanently damaged kidneys. Another report of his observations was published in 1942. His main evidence of the malarial origin of the subacute glomerular nephrosis which he described is the response to quinine, and thus he...

AIMS AND OBJECTIVE To study the clinical, biochemical and histopathological changes in the liver of patients of Plasmodium falciparum malaria with jaundice. MATERIAL AND METHOD This study was conducted on 50 PBF confirmed cases of Plasmodium falciparum malaria with jaundice. Detailed history, clinical examination, biochemical parameters for liver function test and blood for hepatitis B and C ...

Malaria has been in existence since ancient times and for millennia thought to be carried by vapors. Alphonse Laveran made the discovery of the malarial parasite in 1880. The next most important milestone in the history of malaria was the unraveling of the mystery of malaria transmission. Ronald Ross, born in British India and educated as a doctor in England, was working in the Indian Medical S...

Malaria infections in pregnancy are associated with adverse outcomes for both mother and child. There are few data on hyper-reactive malarial splenomegaly, an aberrant immunological response to chronic or recurrent malaria in pregnancy. This retrospective assessment reviewed the impact of mefloquine treatment on pregnant women with suspected hyper-reactive malarial splenomegaly in an area of lo...

Enzyme-linked immunosorbent assays (ELISA) for detecting malarial parasites in blood were tested on uninfected monkeys and in monkeys infected with Plasmodium falciparum. A double antibody sandwich ELISA detected one malarial cell per 10(3) uninfected cells, and an inhibition ELISA detected on infected cell per 10(4) uninfected erythrocytes. These methods are not yet as sensitive as conventiona...