Hereditary hemochromatosis, an iron overload disease associated with excessive intestinal iron absorption, is commonly caused by loss of HFE gene function. Both iron and manganese absorption are regulated by iron status, but the relationships between the transport pathways of these metals and how they are affected by HFE-associated hemochromatosis remain poorly understood. Loss of HFE function ...

the nasirabad manganese deposit is located 5 km south of nasirabad, 8 km sw of neyriz in the fars province. structurally, the area is placed in the southeastern part of zagros thrust belt. in this area, the manganese mineralization occurred as ore layers and nodules, interlayered with pichakun radiolarite chert deposits. in this study, mineralogy and geochemistry of uranium, thorium and lead is...

1. The maximum capacity of the bovine liver to excrete manganese in bile was determined in three Friesian-cross steers surgically prepared to allow bile flow-rate to be measured and samples collected. Plasma Mn concentrations were increased by infusing manganese chloride solutions into a jugular vein and the biliary excretion rates of Mn, copper, zinc and iron were measured. 2. The maximum capa...

A six-coordinate manganese (II) complex with the tripod ligand tris(2-benzimidazolylmethyl)amine (ntb), with composition [Mn(ntb) (4-hydroxycinnamate)](4-hydroxycinnamate) · (DMF)0.5 · (H2O)3, was synthesized and characterized by elemental and thermal analyses, electrical conductivity, IR, and UV/vis spectral measurements. The crystal structure of the complex has been determined by the single-c...

Clickable ligands like N,N'-bis((pyridin-2-yl)methyl)prop-2-yn-1-amine (L(1)) and N-((1-methyl-1H-imidazol-2-yl)methyl)-N-(pyridin-2-ylmethyl)prop-2-yn-1-amine (L(2)) have been used to synthesise a series of manganese(ii) complexes for grafting onto appropriate solid supports. These ligands mimic the 2-His-1-carboxylate facial chelation present in the active site of the manganese-dependent diox...

Motivated by the relatively wide range of values published hitherto, we offer a new, reliable method for determination of manganese in hair from unexposed human subjects. By using a mini-autoclave, we have developed a method that obviates loss of manganese during digestion and, thanks to use of a Teflon receptacle and rigorous methodology, contamination has been minimized. We used Zeeman flamel...

Multinuclear manganese sites that are involved in the catalysis of reactions vital to biological systems are being steadily recognized and studied. Besides the photosynthetic water-oxidizing complex, which is known to utilize 4 Mn ions for the oxidation of water to molecular oxygen [1], evidence has accumulated that the Mn site of the pseudo-catalase from Lactobacillus planatrum is comprised of...

Manganese is an essential metal in human that functions in many enzymes. In contrast excessive exposure to Mn results in neurotoxicity. Accumulation of manganese damages central nervous system and causes Parkinson disease like syndrome called manganism. Mn neurotoxicity has been suggested to involve an imbalance in catecholamine neurotransmitters. It hypothesized that Mn can obstruct catecholam...

A new highly selective iodide electrode incorporating a binuclear manganese(III) complex, bis(salicylaldehyde-aminopropanol)dichloroaceticdimanganese(III) [Mn(III)(2)-BSAPDCA], as a neutral carrier is described. The electrode displays an anti-Hofmeister selectivity sequence: iodide >> perchlorate > salicylate > thiocyanate > nitrate > bromide > nitrite > chloride > sulfate. The excellent select...

We report an in situ soft chemical synthesis of a novel hybrid material, cellulose-nanoscale-manganese oxide composite (C-NMOC), and its application for Pb(II) removal from aqueous solutions. For comparison, detailed Pb(II) adsorption studies were also performed with nanoscale-manganese oxide powder (NMO), prepared through a similar route. Various spectroscopic and microscopic techniques were u...