In the May issue, Major et al. examined trends in adverse events associated with use of prescription and over-the-counter (OTC) acetaminophen products (2009–2012) from data within three national surveillance systems reflecting calls to U.S. Poison Centers, emergency department visits, and hospitalizations. The analysis included changes in the number of adverse events over time as well as trends...

this study empirically examines whether managers manipulate reported income through the timing of sales of long-lived assets and investments. several empirical implications of the income-smoothing and debt-equity hypothesis in the context of asset sales were tested. the findings are consistent with the timing of asset sales by managers so that the recognized accounting income from these sales s...

Data envelopment analysis (DEA) is a powerful tool for measuring the relative efficiencies of a set of decision making units (DMUs) such as schools and bank branches that transform multiple inputs to multiple outputs. In centralized decision-making systems, management normally imposes common resource constraints such as fixed capital, budgets for operating capital and staff count. In consequenc...

This paper develops and tests a new model for multiple-unit adoptions of durable goods based on the diffusion modeling tradition. Multiple-unit adoptions are a major component of sales for many consumer durable product categories. For instance, sales of multiple-unit adoptions for televisions have been high than both first adoptions and replacement purchases since 1977, while for automobiles th...

A number of recent improvements in the engineering of high-titer expression vectors, in biopharmaceutical process development, and in facility construction have converged to present new opportunities for cost-effective, f lexible, biomanufacturing facility construction. The evolution of requirements for biopharmaceutical facilities is driven by globalization of the biopharmaceutical industry, p...

Applications of the Hausdorff space and its mappings into tangent spaces are outlined, including their fractal dimensions and self-similarities. The paper details this theory set up and further describes virtualizations and atomization of manufacturing processes. It demonstrates novel concurrency principles that will guide manufacturing processes and resources configurations. Moreover, varying ...

this research explores the effective ways of sales promotion at liability insurance according to upgrade policies in tehran. the goal is development of planning strategic to help iran insurance industry.  first, we evaluate opinions and views of iran insurance company experts and iran insurance sales agents in tehran on sales promotion (also, priority of the promotion policies) of liability ins...

The concave cost supply management problem consists in optimization of product delivery from a set of providers to the manufacturing units (single unit and single planning period in our case) with respect to delivery cost functions of concave type. Given the lower and upper bounds on the shipment size for each provider, the demand of the manufacturing unit has to be satisfied. In this chapter i...