background: the availability of testis specific genes will be of help in choosing the most promising biomarkers for the detection of testicular sperm retrieval in patients with non-obstructive azoospermia (noa). testis specific chromodomain protein y 1 (cdy1) is a histone acetyltransferase which concentrates in the round spermatid nucleus, where histone hyperacetylation occurs and causes the re...

Background Chronic kidney disease is a global health concern, its detection and diagnosis in earlier stages is also a great challenge that can alleviate this burden. Kidney biopsy is important to establish histopathological patterns. But, it is invasive. We aimedto evaluate the correlation of renal resistive index (RI) measured by Doppler ultrasound with the prog...

The aim of the study was to determine whether the expression of the cell cycle markers p53, MDM2, p21, and Ki-67 was predictive of superficial bladder cancer recurrence and to compare the relative predictive power for tumor recurrence of a cell cycle index based on the number of abnormally expressed cell cycle markers with a clinicopathological index based on primary clinical tumor characterist...

I. Clearance Methods:The concept of renal clearance was introduced as a way of expressing the relation between the excretion per unit time and the concentration in the plasma which is obviously an index of kidneys ability to clear the blood of any substance (1). Measurements of GFR are traditionally based on the renal clearance of a marker in plasma, expressed as the volume of plasma completely...

background: the aim of this study is to compare the circulating placental growth factor (plgf) concentration in women with and without endometrioma to verify the performance of this marker to diagnose the disease. materials and methods: in this case-control study, thirteen women with histological diagnosis of ovarian endometriosis were compared with women without endometriosis disease. plgf pla...

Objective: This study aimed to investigate the value of the neutrophil CD64 index for diagnosing secondary infection in Severe Acute Pancreatitis (SAP) patients. Methods: A total of 43 patients with SAP were enrolled between January 2011 and December 2015. Patient Acute Physiology and Chronic Health Evaluation II and Rason scores were calculated and blood samples were collected to determine the...

septicemia in neonates is the commonest cause of mortality. early recognition and diagnosis of neonatal sepsis remains a challenge because of the variable and nonspecific clinical presentation. the laboratory criteria are often non specific and not fully reliable. the objective of this review is to highlight the various hematological and biological markers of neonatal sepsis. we searched pubmed...

Methods Bone mineral density (BMD) of the lumbar spine and bilateral proximal femurs (dual energy x-ray absorptiometry) and bone metabolism markers {bone formation marker: serum bone alkaline phosphatase (BAP); bone resorption marker: serum tartrate-resistant acid phosphatase serum band 5 (TRAP5b)} were measured in 55 consecutive AIS subjects aged 10 to 18 years-old (mean: 15.6+/-1.7). BMD, bod...

BACKGROUND Prognostic nutritional index has been shown to be a prognostic marker for various solid tumors. However, few studies have investigated the impact of the prognostic nutritional index on survival of patients with breast cancer. The aim of this study was to investigate the impact of the prognostic nutritional index on the long-term outcomes in patients with breast cancer. METHODS This...