Peham is credited (Burket and Abell, 1944) with the report of the first case in 1899 in Germany, but there was no typical masculinization in his case. Bovin (Kepler, Dokerty and Priestly, 1944) reported the first case in America in 1908 and Blair and Bell (Searle et al., 1948) reported the first case in England in 1915. By 1944, Kepler et al. collected 13 cases from the literature and added one...

Disorders of Sex Development (DSD) remain a fascinating challenge for the paediatricians, endocrinologists, biologists, psychiatrists, geneticists, radiologists, surgeons and for the whole society. This article aims at highlighting the current controversies and questions met with genital reconstruction in children born with abnormal genitalia. The main current techniques of masculinization and ...

Müllerian inhibiting factor that induces regression of Müllerian ducts that in females would differentiate into the uterus. These processes for sex determination do not occur in females in the absence of SRY. Sex differentiation related genes such as SOX9, FGF9, DAX1, WT1, RSPO1, and SOX10, which are located on either autosomes or the X chromosome, may have a role in gonad development and funct...

We present a case regarding a 32-year old African male with penoscrotal hypospadias, left cryptorchidism and a left inguinal hernia. There were moderate masculinization characteristics. He underwent a Lichtenstein hernia repair with perioperative biopsies of the left inguinal testis and epididymis. Microscopic examination showed a Sertoli-only left testis with Leydig-cell hyperplasia and the le...

BACKGROUND Transmasculine individuals are people who were assigned as female at birth, but identify on the male side of the gender spectrum. They might choose to use and engage their bodies to be pregnant, birth a baby, and chestfeed. This study asked an open research question, "What are the experiences of transmasculine individuals with pregnancy, birthing, and feeding their newborns?" METHO...

The patient, an unmarried woman of 22 years, presented with a history of irregular periods for four years. From the age of 19 she had developed scanty fine facial hairs, gained weight, and noticed a pronounced increase in her muscular power. Examination showed minimal hirsutism. The blood pressure was 140/80 mm Hg. There were no abdominal striae or palpable masses. Vaginal examination showed no...

Evolutionary theory predicts that sexually antagonistic mutations accumulate differentially on the X chromosome and autosomes in species with an XY sex-determination system, with effects (masculinization or feminization of the X) depending on the dominance of mutations. Organisms with alternative modes of inheritance of sex chromosomes offer interesting opportunities for studying sexual conflic...

This paper explores how the identity of victim-survivors sexual violence is portrayed in dystopian TV series Westworld (2016-present) by analyzing linguistic characterization lead female character, Dolores Abernathy. To do so, this adopts a mixed methodology which combines corpus stylistics and Appraisal Theory with feminist critical reading results order to examine textual cues Dolores’ dialog...