persons infected with the human immunodeficiency virus (hiv) are particularly susceptible to tuberculosis, either by latent infection reactivation or by a primary infection with rapid progression to active disease. this study was done to determine the frequency of tuberculosis infection among iranian patients with hiv/aids. a total of 262 hiv/aids patients attending all three hiv/aids health ca...

OBJECTIVE Under Millennium Development Goal 4, countries are required to reduce child mortality by two-thirds between 1990 and 2015. In countries with generalized epidemics of human immunodeficiency virus (HIV) infection, standard statistics based on fertility history may misrepresent progress towards this target owing to the correlation between deaths among mothers and early childhood deaths f...

Naive T cells in untreated HIV-1 infected individuals have a reduced T-cell receptor excision circle (TREC) content. Previous mathematical models have suggested that this is due to increased naive T-cell division. It remains unclear, however, how reduced naive TREC contents can be reconciled with a gradual loss of naive T cells in HIV-1 infection. We performed longitudinal analyses in humans be...

Background: In patients who are hepatitis B virus (HBV) DNA-positive, but HBV surface antigen (HBsAg) -negative, the infection is referred to as occult hepatitis B infection (OBI). Occult HBV infection is harmful when other liver diseases are present, and can aggravate liver damage in in patients with chronic liver diseases. In human immunodeficiency virus (HIV) infection the suppression of vir...

BACKGROUND Men who have sex with men (MSM) are much more likely to be infected with HIV than the general population. China has a sizable population of MSM, including gay, bisexual men, money boys and some rural workers. So reducing HIV infection in this population is an important component of the national HIV/AIDS prevention and control program. METHODS We develop a mathematical model using a...

background hiv and hcv infections are basic issues of many health systems. since hiv and hcv are transmitted similarly, it is common to become infected by them simultaneously. no consensus exists on the effect of hcv infection on the survival of hiv-infected patients. objectives this study aimed to investigate the issue in a relatively large cohort of patients who had a high prevalence of this ...

background: pulmonary tuberculosis is still the most common form of tuberculosis in hiv infected patients having differ­ent presentations according to the degree of immunosuppression. this study appraised the impact of hiv infection on clini­cal, laboratory and radiological presentations of tuberculosis. methods: the clinical, laboratory and radiological presentations of pulmonary tb in 56 hiv-...

As HIV-1 envelope immune responses are critical to vaccine related protection, most candidate HIV vaccines entering efficacy trials are based upon a clade specific design. This need for clade specific vaccine prototypes markedly reduces the implementation of potentially effective HIV vaccines. We utilized a mathematical model to determine the effectiveness of immediate roll-out of a non-clade m...