Abstract A fast, effective and low cost sample preparation method based on miniaturized matrix solid-phase dispersion (micro-MSPD) combined with gas chromatography coupled to tandem triple-quadrupole-mass spectrometry (GC–MS/MS) has been developed for the determination of six phthalate diesters (DMP, DEP, DBP, BzBP, DEHP DnOP) in mussel samples. The target compounds have included list priority ...

Neste estudo, um eficiente método, a dispersão da matriz em fase sólida (DMFS), foi usado para a determinação simultânea de furanocoumarinas de frutos de Archangelica officinalis Hoffm. Amostras da planta foram preparadas pelo procedimento MSPD otimizado, utilizando C18 como sorvente. A análise foi realizada por cromatografia líquida de alta eficiência com detector de arranjo de diodos (HPLC-DA...

A high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/ MS) method was established for the determination of inabenfide in fruits, vegetables, tea, honey, cereals and animal-derived foods. The food samples were extracted with acetonitrile, then purified by dispersion solid phase extraction using primary secondary amine (PSA) and C18 as solid phase. The residue was determined ...

The aim of this work was to evaluate the role of cyclodextrins in topical drug formulations. Solid piroxicam (PX) complexes with beta-cyclodextrin (beta-CD) and randomly methylated beta-cyclodextrin (RAMEB) were prepared by freeze-drying and characterized using differential scanning calorimetry (DSC), X-ray powder diffractometry (XRPD), Fourier transform infrared spectroscopy (FTIR) and near in...