A new series of 5-(indole-2-yl)-3-substituted 1,2,4-oxadiazoles were synthesized and evaluated for their anticancer activities. Structures of the compounds were confirmed by spectroscopic methods. Structural modifications were done to improve the antiproliferative activity of compound 1. The results indicated that a benzyloxyl substituent on the C-4 position was better than a methyl substituent...

STATEMENT OF PROBLEM Agenesis of the maxillary lateral incisor has been linked to differences in the size of the remaining teeth. Thus, the mesiodistal space required for definitive esthetic restoration in patients with missing maxillary lateral incisors may be reduced. PURPOSE The purpose of this study was to determine whether a tooth size discrepancy exists in orthodontic patients with agen...

Objective. This study aimed to find out the change in esthetic ratios during rotation of patient's head using a simulation. Materials and Methods. A plaster study model was photographed placing its midline along the long axis of the camera. Then a series of photographs were taken by rotating the model each degree till 10° on both right and left sides. These photographs were digitally measured a...

A ten year old boy came with a chief complaint of unerupted permanent maxillary right central incisor. Deciduous right central and lateral incisors were retained. Radiographic examination revealed an inverted and dilacerated mesiodens with the root bent over the incisal surface of the right central incisor preventing its eruption. An occlusal radiograph and radiographs using shift cone techniqu...

Adenomatoid odontogenic tumor (AOT), a benign (hamartomatous) lesion of odontogenic origin, is an uncommon tumor which affects mainly females in the second decade. This lesion is most commonly associated with an impacted maxillary canine. This paper reported a case of AOT, in a 16-year-old female, associated with an impacted maxillary left lateral incisor. The evolution of this tumor was follow...

INTRODUCTION Maxillary canine-first premolar transposition (Mx.C.P1) is an uncommon dental positional anomaly that may create many orthodontic problems from both esthetic and functional points of view. OBJECTIVE In this report we show the orthodontic management of a case of Mx.C.P1 associated with bilateral maxillary lateral incisor agenesis and unilateral mandibular second premolar agenesis ...

This article reports a clinical case of a 13-year-old girl, who was referred with chief complaint of a non-esthetic maxillary central incisors position. Five years ago, her maxillary right and left central incisors and left lateral incisor intruded into the maxilla. The intruded teeth were splinted for a month. After splint removal, the patient lost follow up. The aim of this work is to report ...

A talon cusp is a dental anomaly commonly occurring in the permanent dentition compared to the primary dentition. It commonly affects the maxillary anterior teeth. In primary dentition, the most commonly affected tooth is the maxillary central incisors. This is a rare case report of a 5-year-old male patient with a talon cusp affecting the mandibular primary lateral incisor. Recognition and tre...