Although model-based fault tolerant control (FTC) has become prevalent in various engineering fields, its application to air-conditioning systems is limited due to the lack of controloriented models to characterize the phase change of refrigerant in the vapor compression cycle. The emergence of moving boundary method (MBM) illuminates a promising way for FTC design. In this paper, we exploit a ...

This paper sketches several aspects of a hypothetical cortical architecture for visual object recognition, based on a recent computational model. The scheme relies on modules for learning from examples, such as Hyperbf-like networks, as its basic components. Such models are not intended to be precise theories of the biological circuitry but rather to capture a class of explanations we call Memo...

Periosteal chondrosarcoma (PC) is a rare low-grade malignant cartilaginous tumor originating on the bone surface. Wide surgical resection is the recommended treatment. Prognosis is usually good if surgery is adequate. Metastasis is late and very rare. We present the clinical, radiographic, and pathological features of a PC accompanied with fibular cortical invasion in a 30-year-old woman. Wide ...

To improve the endurance and charging flexibility of electric vehicle battery packs, this paper proposes a multi-battery block module (MBM) topology for four-phase switched reluctance motors (SRMs), which not only allows flexible operation, but also achieves fast demagnetization excitation. By integrating photovoltaic (PV)panel into an asymmetrical half-bridge (AHB)converter, MBM is designed to...

Motivated by the need for readily available data for testing an open-source health information exchange platform, we developed and evaluated two methods for generating synthetic messages. The methods used HL7 version 2 messages obtained from the Indiana Network for Patient Care. Data from both methods were analyzed to assess how effectively the output reflected original 'real-world' data. The M...

On April 29, 2015, the neuroscience community lost an accomplished and beloved scientist when Dominique Muller died in an accident in the French Alps south of Grenoble. He passed away doing his favorite pastime: plane gliding. Dominique had a fiery curiosity that is at the heart of good science. He lived his passion for research in the laboratory, combining experimental creativity, warm mentors...

Prediction of clinical efficacy, toxicity, and drug-drug interactions may be improved by accounting for the intracellular unbound drug concentration (Cunbound) in vitro and in vivo. Furthermore, subcellular drug distribution may aid in predicting efficacy, toxicity, and risk assessment. The present study was designed to quantify the intracellular Cunbound and subcellular localization of drugs i...

Institute of Environmental Systems Barbarastraße 12, D-49076 Osnabrueck, Ge 2 38 64 3668 Department of Biology/Chemistry, Divisio Barbarastraße 13, D-49076 Osnabrueck, Ge Environmental Mineralogy, Institute for Ap Darmstadt, Schnittspahnstr. 9, D-64287 Da † Electronic supplementary informa 10.1039/c3em00214d ‡ Present address: Water, Environment an Recherches Géologiques et Minières (BRG 36009,...

Abstract PURPOSE Patients with BRAF-mutant melanoma brain metastases (MBM) continue to have limited overall survival (OS), averaging 4 months, despite advancements in systemic therapies. Our study aims identify patient-specific and treatment-related prognostic factors MBM inform treatment sequencing patient selection future studies improve outcomes. METHODS The following data were manually cura...