McCune-Albright syndrome (MAS) is characterized by the triad of fibrous dysplasia (FD), cafe-au-lait spots and precocious puberty (PP). We report a 14-year-old girl with MAS who has been followed-up for 8 years. She was referred for multiple fractures and vaginal bleeding at age 5.9 years. She had peripheral PP, FD, and osteoporosis and was diagnosed as MAS. The patient was treated with aromata...

The McCune-Albright syndrome was described as a syndrome of polyostotic fibrous dysplasia, café au lait skin pigmentation, and autonomous endocrine hyperfunction in 1937. We report a 17-year girl with early menarche and accelerated growth for the past three years. The endocrinological examination showed slight rise of growth hormone with other hormones in normal range. The CT showed an expansiv...

Dr. Raphael Vicente Alves – Rua Estado de Israel 907 / 31 04022-002 São Paulo SP Brasil. E-mail: [email protected] Co-existing fibrous dysplasia and meningothelial meningioma is extremely rare. A search at “PubMed” (U.S. National Library of Medicine) with terms “fibrous”, “dysplasia” and “meningioma” demonstrated a total of 7 cases reported. Three cases in association with McCune-Albri...

Sujit S. Phatak DJ McCune George Saikalis, Ph.D. Yasuo Sugure OVERVIEW: The need for CPSs derives from the complexity of modern automotive embedded systems, which can contain more than 100 ECUs, a large ROM capacity, and a large amount of software code. Another issue is that traditional design methodologies find it difficult to cope when fundamental hardware problems are identified late in the ...

Pseudohypoparathyroidism due to deficient end organ response to parathyroid hormone (PTH) is characterized by hypocalcemia, hyperphosphatemia and increased serum PTH. We report a case of an 8-year-old girl with pseudohypoparathyroidism without features of Albright's hereditary osteodystrophy. The case is of interest as the child on serial follow-up over a period of 2 years developed hypothyroid...