Measles remains an important cause of child mortality, although the numbers of measles-related deaths has decreased during the last decade [1] through childhood immunisation programmes and follow-up measles vaccine campaigns. In 2005, the World Health Organization (WHO) and the United Nations Children’s Fund (UNICEF) launched a global plan to further reduce measles mortality in the years 2006–2...

Introduction: Measles is a contagious disease which is passed on easily from a person to the other. Today, although, the number of measles cases have been decreased dramatically, but it is still a common disease. The aim of this research is to study the patients with measles in Khorramabad city. Materials and Methods: This cross – sectional study was carried out on 124 patients who were adm...

background: decay of vaccine–induced antibody titres without boosting of the wild measles virus has been well documented. revaccination against measles has reduced the prevalence of the disease worldwide. revaccination may cause ige induced anaphylaxis. objective: to study measles igg antibody in revaccinated populations and its relation to ige induced hypersensitivity. methods: blood samples w...

Introduction . The implementation of the WHO Measles Elimination Program has yielded serious results, but in recent years an increase incidence rate this infection been observed. In particular, according to WHO, 2019 vs. 2018 measles morbidity was elevated by 3-fold worldwide. While investigating outbreaks among patients, apart from unvaccinated subjects, a substantial group adults vaccinated c...

There is a complex inter-relationship between nutrition and morbidity in human health. Many diseases reduce nutritional status, but on the other hand, having low status also known to make individuals more susceptible certain serious illness. Modern evidence these relationships, determined after introduction of antibiotics vaccines, may not be applicable historical settings before medical techno...

Background: Measles is a contagious respiratory viral infection that accompanied with skin rash. Vaccination against measles has reduced the prevalence of the disease but sporadic measles epidemic still occurred in young people. This study, was carried out for the response evaluation of immunity against measles in Iranian soldiers living in garrisons. Methods: In this study based on the history...

conclusions results indicated that the present vaccination program is insufficient for immunity against measles in this area. the general population immunity was lower than the necessary level for the elimination of measles. therefore, sero-epidemiological studies are necessary to organize national programs for control and elimination of measles. results overall, 821 (91.2%) of the studied popu...

Measles still remains a major cause of childhood morbidity and mortality worldwide. Measles virus (MV) vaccines are highly successful, but the mechanism underlying their efficacy has been unclear. Here we report the crystal structure of the MV attachment protein, hemagglutinin, responsible for MV entry. The receptor-binding head domain exhibits a cubic-shaped beta-propeller structure and forms ...

Measles virus (MV) efficiently causes generalized immunosuppression which accounts to a major extent for cases of measles-asscociated severe morbidity and mortality. MV infections alter many functions of antigen presenting cells (APC) (dendritic cells (DCs)) and lymphocytes, yet many molecular targets of the virus remain poorly defined. Cellular interactions and effector functions of DCs and ly...

Studies in animal models and cell lines show that vitamin A and related retinoids play a major role in immunity, including expression of mucins and keratins, lymphopoiesis, apoptosis, cytokine expression, production of antibody, and the function of neutrophils, natural killer cells, monocytes or macrophages, T lymphocytes and B lymphocytes. Recent clinical trials suggest that vitamin A suppleme...