The drift velocities of spiral waves driven by a periodic mechanic deformation or a constant or periodic electric field are obtained under the weak deformation approximation around the spiral wave tip. An approximate formula is derived for these drift velocities and some significant results, such as the drift of spiral waves induced by a mechanical deformation with v53v0 , are predicted. Numeri...

Recently, it was reported that rabbit and human red blood cells (RBCs) release ATP in response to mechanical deformation. Here we investigate the hypothesis that the activity of the cystic fibrosis transmembrane conductance regulator (CFTR), a member of the ATP binding cassette, is required for deformation-induced ATP release from RBCs. Incubation of rabbit RBCs with either of two inhibitors of...

The structure and mechanical properties of crystalline materials of three boron difluoride dibenzoylmethane (BF2dbm) derivatives were investigated to examine the correlation, if any, among mechanochromic luminescence (ML) behaviour, solid-state structure, and the mechanical behaviour of single crystals. Qualitative mechanical deformation tests show that the crystals of BF2dbm( (t) Bu)2 can be b...

It is becoming clear that mechanical stimuli are crucial factors in regulating the biology of the cell, but the short-term structural response of a cell to mechanical forces remains relatively poorly understood. We mechanically stimulated cells transiently expressing actin-EGFP with controlled forces (0-20 nN) in order to investigate the structural response of the cell. Two clear force-dependen...

In this work, plastic deformation was locally introduced at room temperature by 12 nanoindentation on a γ-TiAl based alloy. Comprehensive analyzes of microstructures were 13 performed before and after deformation. In particular, the Burgers vectors, the line directions and 14 the mechanical twinning systems were studied via accurate electron channeling contrast imaging. 15 Accommodation of the ...

= Abstract = To investigate why calcification is accelerated by mechanical flexure, in vitro calcification of segmented polyurethane (SPU) under static elongation and dynamic mechanical flexure was performed. After the calcification period, the amount of calcium deposition was increased by elongation, but the amount of calcium deposition per unit area of the elongated surface was relatively sma...

A functionally graded material beam with generalized boundary conditions is contemplated in the present study in order to examine the deformation and stress behavior under thermal and thermo-mechanical load. Three discrete combinations of functionally graded materials have been deliberate in including a wide range of materials and material properties. The variation of material properties has be...

Our bodies are in constant motion and so are the neurons that invade each tissue. Motion-induced neuron deformation and damage are associated with several neurodegenerative conditions. Here, we investigated the question of how the neuronal cytoskeleton protects axons and dendrites from mechanical stress, exploiting mutations in UNC-70 β-spectrin, PTL-1 tau/MAP2-like and MEC-7 β-tubulin proteins...

Living cells can sense mechanical forces and convert them into biological responses. Similarly, biological and biochemical signals are known to influence the abilities of cells to sense, generate and bear mechanical forces. Studies into the mechanics of single cells, subcellular components and biological molecules have rapidly evolved during the past decade with significant implications for bio...