Cardiogenic shock (CS) is a life-threatening condition associated with significant morbidity and mortality. Pharmacological therapy is often the first line of treatment but mechanical support can provide substantial hemodynamic improvement in refractory CS. Percutaneous mechanical support devices are placed in a minimally invasive manner and provide life-saving assistance to the failing myocard...

Shock is a state of acute circulatory failure leading to decreased organ perfusion, with inadequate delivery of oxygenated blood to tissues and resultant end-organ dysfunction. The mechanisms that can result in shock are divided into 4 categories: (1) hypovolemic, (2) distributive, (3) cardiogenic, and (4) obstructive. While much is known regarding treatment of patients in shock, several contro...

Although we rarely see a shock wave in everyday life, we experience them upon hearing the sound of an explosion, the bang of a gunshot, or the crack of a whip. In addition, objects that travel at supersonic speeds, such as bullets and missiles, also generate shock waves. During a typical shock-loading process, large pressures generated at the shock front can lead to an increase in the reactants...

OBJECTIVE Cardiogenic shock remains an important therapeutic challenge, with high in-hospital mortality rates. Mechanical circulatory support may be beneficial in these patients. Since the efficacy of the intra-aortic balloon pump seems limited, new percutaneously placed mechanical left ventricular support devices, such as the Impella system, have been developed for this purpose. Our current pu...

BACKGROUND Echocardiographic myocardial dysfunction is reported commonly in sepsis and septic shock, but there are limited data on sepsis-related right ventricular dysfunction. This study sought to evaluate the association of right ventricular dysfunction with clinical outcomes in patients with severe sepsis and septic shock. METHODS Historical cohort study of adult patients admitted to all i...

1.1 Acute cardiac collapse Patients with cardiogenic shock and cardiac arrest still have a very poor prognosis despite recent improvements in treatment algorithms. Acute coronary ischemia and myocardial infarction (AMI) is the most frequent cause of cardiogenic shock and cardiac arrest. Improved survival has been shown for patients with AMI treated with urgent coronary revascularization. Also, ...

OBJECTIVES The aim of this study was to assess the impact of gender on clinical course and in-hospital mortality in patients with cardiogenic shock (CS) complicating acute myocardial infarction (AMI). BACKGROUND Previous studies have demonstrated higher mortality for women compared with men with ST elevation myocardial infarctions and higher rates of CS after AMI. The influence of gender and ...

Dynamic analysis of aerospace systems is required to insure that the structures will maintain their integrity and provide predictable and acceptable mechanical performance throughout the mission profile of specified acceleration environments. This analysis includes the structural response to shock and vibration and evaluates the maximum deflections and material stresses and the potential for th...

Postinfarction ventricular septal defect (PIVSD) is a devastating mechanical complication following acute myocardial infarction. The management of this pathology is quite challenging, especially in case of complicated cardiogenic shock. The difficulties lie in the timing and type of intervention. Debates exist with regard to immediate versus deferring repair, as well as open repair versus percu...