نتایج جستجو برای: mechanistic system

تعداد نتایج: 2268268  

2017
John J. Jamieson Peter C. Searson Sharon Gerecht

The blood-brain barrier (BBB) is the interface between the vasculature and the brain, regulating molecular and cellular transport into the brain. Endothelial cells (ECs) that form the capillary walls constitute the physical barrier but are dependent on interactions with other cell types. In vitro models are widely used in BBB research for mechanistic studies and drug screening. Current models h...

2015
Alexander T Murray Myles J H Dowley Fabienne Pradaux-Caggiano Amgalanbaatar Baldansuren Alistair J Fielding Floriana Tuna Christopher H Hendon Aron Walsh Guy C Lloyd-Jones Matthew P John David R Carbery

The flavoenzyme monoamine oxidase (MAO) regulates mammalian behavioral patterns by modulating neurotransmitters such as adrenaline and serotonin. The mechanistic basis which underpins this enzyme is far from agreed upon. Reported herein is that the combination of a synthetic flavin and alloxan generates a catalyst system which facilitates biomimetic amine oxidation. Mechanistic and electron par...

Journal: :Journal of General Physiology 2008

Journal: :Current Opinion in Toxicology 2019

Journal: :Journal of Nutrition, Food Research and Technology 2019

Journal: :Turkish Journal of Pharmaceutical Sciences 2021

Journal: :The Journal of the Acoustical Society of America 1959

Journal: :Journal of the American Statistical Association 2014

Journal: :European Heart Journal 1997

Journal: :Journal of Biological Chemistry 2006

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