Many users and applications require the integration of semistructured data from autonomous, heterogeneous Web sources. Over the last years mediator systems have emerged that use domain knowledge to overcome the problem of structural heterogeneity. However, many users of these systems do not have a thorough knowledge of the complex global schemas and of the comprehensive query languages. Consequ...

The mediator protein Claspin is critical for the activation of the checkpoint kinase Chk1 during checkpoint responses to stalled replication forks. This function involves the Chk1-activating domain (CKAD) of Claspin, which undergoes phosphorylation on multiple conserved sites. These phosphorylations promote binding of Chk1 to Claspin and ensuing activation of Chk1 by ATR. However, despite the i...

OBJECTIVES The study investigated self-efficacy as a possible mediator of the relationship between the social support and depressive symptoms of primarily informal caregivers, mainly family members, of patients with dementia in Hong Kong. METHOD One hundred and thirty-four caregivers were interviewed. Path analyses were conducted using a self-efficacy scale that consists of three subscales as...

The integration of heterogenous web sources is still a big challenge. One approach to deal with integration problems is the usage of domain knowledge in form of vocabularies or ontologies during the integration (mapping of source data) as well as during query processing. However, such an ontology-based mediator system still have to overcome performance issues because of high communication costs...

The tourism industry is a good candidate for taking up Semantic Web technology. In fact, there are many portals and websites belonging to the tourism domain that promote tourist products (places to visit, food to eat, museums, etc.) and tourist services (hotels, events, etc.), published by several operators (tourist promoter associations, public agencies, etc.). This article presents how the MO...

The Web catalogs like Yahoo! and Open Directory are very useful for browsing and querying the Web. Although they index only a fraction of the pages that are indexed by search engines these catalogs are hand-crafted by domain experts and are therefore of high quality. We present a model for building mediators over Web catalogs, so as to provide users with cus-tomized views of such catalogs. We f...

We address the problem of data and information interoperability in the Earth System Science information domain. We believe that well-established architectures and standard technologies are now available to implement data interoperability. In particular, we elaborate on the mediated approach, and present several technological aspects of our implementation of a Mediator-based Information System f...

This paper suggests a new integrative perspective on business – IT alignment as IT is becoming entwined with almost all business functions. As a consequence, the strategic value of IT is decreasing and IT is becoming a commodity. Therefore, we argue that the IT strategy domain in the Strategic Alignment model can be merged with business strategy and propose processes as the mediator between bus...

Objectives. The objective of this study is threefold: 1) to examine the effect positive illusions on risk taking manifested in opportunity evaluation and investment decision; 2) mediating role attitudes relationship between 3) moderating experience decision. Sample setting. Research sample comprised 132 entrepreneurs aged 19 63 (M = 40.6; SD 10.8) owning small, medium, large-sized businesses. H...