The clinical course of HIV infection is described by Redfield and Burke at Walter Reed Army Institute of Research; they stress that AIDS is only a late manifestation of the progressive viral illness. The two authors divide the course of the infection into six stages, with consideration of the T4 cell count throughout. This strategy ties in directly with the next chapter by Weber and Weiss on th...

Since Watson & Crick's 1953 description of the structure of DNA, significant progress has been achieved in the control of congenital disorders, most of which has benefited industrialized countries. Little advantage accrued to developing nations, most of which in the same time frame achieved a significant epidemiological transition, resulting in congenital disorders attaining public health signi...

This volume is the eighth edition of a book which first appeared in 1940. The science of genetics has changed much since then, and so has the book. For the second time it has Dr. Marcus Pembrey as joint author. Developed to fill a void in the field of medical genetics, the book continues to meet a need in the education of physicians. It aims to show how the science of human genetics plays an im...

a series of new concepts about the nlature of inherited variations in huinaii biochemistry which are now part of our thinking in I)iochemical genetics. It is interesting that these concepts, formulated by a practising physician, were largely neglected until in a new climate of thinking they were in part rediscovered by scientists working with totally different material. Only in the last decade ...

Acknowledgements: The additional participating principal investigators of the Amsterdam BHD working group were Marianne A. Jonker (Dept of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam the Netherlands), Arjan C. Houweling (Dept of Clinical Genetics, VU University Medical Center), Quinten Waisfisz (Dept of Clinical Genetics, VU University Medical Center), Johannes J.P. ...

As we unveil our first issue of 2014, we would like to announce the launch of a new feature of Molecular Genetics and Genomic Medicine: “Genetics and Genomic Medicine around the World.” These articles will focus on various aspects of genetics and genomic medicine internationally. Trends in different countries will be described by a senior colleague from that country. In 1988, the Journal of Med...