In the context of PROTECT European project, we have developed an ontology of adverse drug reactions (OntoADR) based on the original MedDRA hierarchy and a query-based method to achieve automatic MedDRA terms groupings for improving pharmacovigilance signal detection. Those groupings were evaluated against standard handmade MedDRA groupings corresponding to first priority pharmacovigilance safet...

Epilepsy is the only neurological condition for which electroencephalography (EEG) primary diagnostic and important prognostic clinical tool. However, manual inspection of EEG signals a time-consuming procedure neurologists. Thus, intense research has been made on creating machine learning methodologies automated epilepsy detection. Also, many or medical facilities have published databases epil...

The knowledge of heart and respiratory rates (HRs RRs) is essential in assessing human body static. This has been associated with many applications, such as survivor rescue ruins, lie detection, emotion detection. Thus, the vital signal extraction from radar echoes after pre-treatments, which have applied using various methods by researchers, exceedingly become a necessary part its further usag...

The Sentinel Initiative aims to develop a national, electronic network to link data on 100 million patients from multiple existing health care data systems by 2012 in order to conduct post-licensur e safety monitoring of FDA-regulated medical products. A critical component of this Initiative is determining what statistical methods can bes t be employed within this framework to accurately, robus...

Ultrasonic detection has many applications in military, medical, marine biology, and physics domains. This paper presents then an emitting signal design for several immersion applications such as liquid level measurement, wall detection for submarine robots, and fish species behavior study. The designed and realized circuits are very simple, of flexible use, and cost-effective. Sensor sealing p...

background: fetal heart rate (fhr) extracted from abdominal electrocardiogram (ecg) is a powerful non-invasive method in appropriately assessing the fetus well-being during pregnancy. despite significant advances in the field of electrocardiography, the analysis of fetal ecg (fecg) signal is considered a challenging issue which is mainly due to low signal to noise ratio (snr) of fecg. objective...