MEN IIB: It is associated with pheochromocytoma, mucosal ganglioneuromas, and marfanoid habitus. This syndrome also presents medullary carcinoma and pheochromocytoma, but only rarely will have hyperparathyroidism. Inheritance isautosomal dominant as in MEN IIA. MEN IIB patients usually get medullary carcinomaearly in life, diagnosed in infancy or early childhood before their 30s, and males andf...

Background: Breast cancer is the most common among women and one of important causes death them. The present study tries to evaluate demographic, clinical, pathological profile female breast patients in Kashmir Methods: This was done government medical college Srinagar, department radiation oncology. A retrospective review 84 treated between January 2021 March 2023 done. Results: total were tak...

Immunohistochemical studies were conducted in 20 cases of canine thyroid tumours. On histological grounds the tumours included four well-differentiated follicular and four well-differentiated medullary carcinomas. Four tumours were suspected to be of possible follicular origin but were poorly-differentiated or anaplastic (undifferentiated); similarly six tumours that were poorly-differentiated ...

Familial medullary carcinoma of the thyroid gland is often associated with phaeochromocytoma; this condition is known as Sipple syndrome. The rate of progression of the disease and the degree of malignancy of the medullary carcinoma may vary from family to family. Thus the nature and behaviour of this disease in any particular family influences the management of the thyroid carcinoma component....

Two patients are reported in whom initial misdiagnoses of medullary cancer or trabecular hyaline adenoma for papillary carcinoma were made.

The one-day ETA-CRN meeting, preceding the ETA meeting in Lisbon, was planned in advance to provide a thorough assessment of the European response to the published American Thyroid Association MTC guidelines. During the meeting, following each of the European speakers, a series of questions, related to the specific aspect, were presented to the audience. The responses from the audience were col...

Plasma carcinoembryonic antigen (CEA) levels were measured by the Z-Gel technique in 138 patients with benign thyroidopathies, 25 patients with thyroid cancer, and 141 normal persons. Levels were raised (above 5 ng/ml) in 2% of the normal subjects, in none of the patients with benign thyroidopathies, and in 20% of the patients with thyroid cancer. They were considerably raised in all cases of m...

Medullary thyroid carcinoma accounts for 5-10% of all thyroid cancers. It is sporadic in 75% of cases and familial in 25% of cases. Germ-line REarranged during transfection (RET) proto-oncogene mutations are detected in more than 95% of patients with familial medullary carcinoma whereas somatic RET mutations are detected in 40-70% of sporadic medullary carcinomas. Surgery is the only curative t...

We report an unusual case of a young male with cerebellar hemangioblastoma treated previously for medullary carcinoma of thyroid, whose PET/CT scans revealed a constellation of findings that suggested the rare Von Hippel Lindau syndrome. The diagnosis was clinched by confirming the findings on whole body contrast enhanced computed tomography (CECT) and contrast enhanced magnetic resonance imagi...

Our preliminary experience of Somatostatin Receptor Positive Tumour Scintigraphy (SRPTS) in the management of some rare neuroendocrine tumours is highlighted. Six patients were evaluated using SRPTS. A single patient each with Zollinger-Ellison syndrome, recurrent medullary carcinoma of thyroid and Stage IV neuroblastoma. Two patients with phaeochromocytoma, and one patient with suspected insul...