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background: leishmaniasis is a parasitic disease caused by different species of leishmania parasites with a wide range of clinical manifestations . antimonial compounds such as meglumine antimoniate (glucantime) are the first line drugs for the treatment of leishmaniasis. however, according to reports of the drug resistance of parasites, the efficacy of antimonial compounds is low. the atp-bind...

this case report states a 25-year-old woman, residing in the city of dezfool, khuzestan province, south of iran with the diagnosis of cutaneous leishmaniasis in june 2008. her skin lesion had de­veloped from 8 months earlier as a nodule on her left arm, 1×3 cm in diameter. because of sever­ity of the lesion, we prescribed meglumine antimoniate intralesionally with giving up her breast feeding. ...

The term leishmaniasis comprises a group of diseases caused by different species of a protozoon called Leishmania. Leishmaniasis is found worldwide, and is considered to be endemic in 88 countries. There are three main clinical forms of leishmaniasis: visceral leishmaniasis, cutaneous leishmaniasis and mucocutaneous leishmaniasis. Exclusive involvement of the mucosa is very rare. We present a s...

A comparison of an indirect immunofluorescence test using promastigotes (IFATp) or cultured amastigotes (IFATa) in the diagnosis and follow-up of canine leishmaniasis caused by Leishmania infantum was carried out. Results obtained with both diagnostic methods were in good agreement although the IFATa titration was more sensitive than the currently used IFATp without losing specificity. The high...

background: pentavalent antimonials are still the first choice treatment for leishmaniasis, but with low efficacy and resistance is emerging. in the present study, the effect of meglumine antimoniate (ma, glucantime) combined with paromomy-cin, miltefosine or allopurinol on in vitro susceptibility of leishmania tropica resistant isolate was evaluated. method : the drugs were obtained from comme...

herein, a 28-year-old man with hoarseness, skin and oral lesions is presented. at the time of admission, the patient had an erythematous plaque on his chin near his lower lip and an erythematous-violaceous plaque on his palate near the open-ing of the pharynx and 20 kg weight lost in last one year. the biopsy of his skin lesions by hematoxylin and eosin staining revealed an infiltration of the ...

We report a case of an unusual presentation of American Tegumentary Leishmaniasis involving a male patient with a solitary lesion on the ear lobe, persisting with minimal increase for at least six months without ulceration or related symptoms. The histological sections showed epithelial atrophy and a large number of structures consistent with Leishmania sp. amastigotes within macrophages. Treat...

BACKGROUND Febrile illnesses like malaria, typhoid, and tuberculosis are the commonest problems in our area, but visceral leishmaniasis (VL) is also one of the diseases presenting with fever in this part of the country. This study was conducted to evaluate its clinical spectrum and way of management. METHODS This study was conducted in Paediatric Department of Women and Children Hospital and ...