This article focuses on developments in pigmentary disorders that extend dermatologists' understanding of the field. Areas that are reviewed include the basic biochemistry, pharmacology, and physiology of the melanocortin system; melanosome development; genetic diseases associated with pigmentary disorders; pigmentary disorders secondary to systemic disease; drug-induced hyperpigmentation; envi...

: Melasma is one of the most common causes hyperpigmentation and a prevalent cosmetic concern for patients. Tranexemic acid an effective mode treatment available in both oral topical forms. To evaluate compare therapeutic effectiveness tranexamic melasma. A total 84 patients who presented to dermatology OPD with melasma were divided into two groups, namely B. Group treated 250 mg twice daily, B...

Introduction: Melasma is an acquired pigmentation disorder characterized by symmetrical hyperpigmented patches, most commonly seen on the face. and iron deficiency are common in women of reproductive age. Iron causes a decrease ferritin levels, which stores body. The mechanism causing melasma thought to be due cell hypoxia tissue involving mediators that increase melanogenesis. This study aims ...

Vyanga (Melasma) is condition of localized hypermelanosis which affect face, and continues to be challenging problem as it causes immense mental stress depression. In ayurvedic texts there lot ahara, aushadha, vihara were mentioned enhance external beauty such varnya varg told by Acharya Charak, romsanjanan etc Shushrut. Melasma can correlated with in Ayurveda. The present study was aimed evalu...

Background Melasma is a common disorder of pigmentation, characterized by symmetric brown or brown-gray patches in sun-exposed facial areas. Hydroquinone (HQ) is the most effective agent in melasma treatment; however it has some adverse events (AE) that limit its extensive use. We evaluated the clinical response of aminoacid filaggrin-based antioxidants (AFBA) in Mexican patients with centrofac...