Tranexamic acid is a novel treatment option for melasma; however, there is no consensus on its use. This systematic review searched major databases for relevant publications to March 2016. Eleven studies with 667 participants were included. Pooled data from tranexamic acid-only observational studies with pre- and post-treatment Melasma Area and Severity Index (MASI) showed a decrease of 1.60 in...

INTRODUCTION Extracts of the tropical fern Polypodium leucotomos appear to possess beneficial properties for the skin attributed to the presence of numerous compounds within the extract that have antioxidant and photoprotective properties. Orally administered Polypodium leucotomos may provide protection against the detrimental photoaging effects of sunlight and can also help reduce the frequenc...

BACKGROUND Low-fluence 1,064 nm Q-switched Nd:YAG laser has been widely used for the treatment of melasma. Although new Q-switched Nd:YAG lasers with photoacoustic twin pulse (PTP) mode have been recently developed for high-efficiency, there is limited information available for the new technique. OBJECTIVE This study was designed to investigate the efficacy and adverse effects after few sessi...

Introduction: Melasma is the main cause of facial hyperchromia and has a signifi cant psychosocial impact. Wood ́s lamp has been a useful device to estimate the depth of melanin determined by light-induced fl uorescence. A dermoscope enables a clear visualization of pigments distribution, and the color variation of melanin will depend on its location within the skin. Objective: Evaluate the clas...

Melasma is a cosmetic disorder with profound psychological impact. Multiple therapies are available for melasma but no therapy the gold standard. The most of patients suffer from relapses and recurrences which force patient to opt over-the-counter medications containing topical steroids or indigenous medications. Use these has led emergence complicated cases refractory treatment. Along hyperpig...

The aim of this study was to determine the impact of melasma on quality of life (QoL) using the dermatology life quality index (DLQI) questionnaire in a group of outpatients. This study is questionnairebased. A total of 101 Turkish women suffering from melasma, who themselves were able to understand and complete the Turkish version of the DLQI questionnaire, were enrolled. This questionnaire in...

in this study demographic, clinical, paraclinical, microbiological, and therapeutic features of patients with community-acquired acute bacterial meningitis admitted to a referral center for infectious diseases in iran, have been evaluated. medical records of adult (> 18 years) individuals with confirmed diagnosis of community-acquired bacterial meningitis during a 4-year period were retrospecti...

introduction: esophagus cancer is most common gi malignancies in zahedan. this investigation was undertaken to define the epidemiology, and prognostic factors relevant to patients withesophagus cancer in this region. methods : we did a retrospective review of 175 patientswith esophagus cancer who presented to ali ebne abitaleb hospital and khatam alanbia hospitalin 2005-2010. data analysis was ...

Background and aim: Melasma is an acquired, symmetric hyperpigmentation, specially in sun-exposed skin. Disorders of thyroid gland result from processes that stimulate the overproduction or underproduction of thyroid hormones. This study was performed to assess the association of melasma with thyroid disorders.Materials and Methods: This case-control study was performed...