Mammalian enabled (Mena) is a member of a protein family thought to link signal transduction pathways to localized remodeling of the actin cytoskeleton. Mena binds directly to Profilin, an actin-binding protein that modulates actin polymerization. In primary neurons, Mena is concentrated at the tips of growth cone filopodia. Mena-deficient mice are viable; however, axons projecting from interhe...

context this systematic review and meta-analysis was performed to determine the prevalence (by overall relative frequency) and clinical information of the behcet’s disease in middle east and north africa (mena) and it has an important effect on the health policy and performing complementary studies in future. evidence acquisition we performed this systematic literature review from several datab...

the main purpose of this paper is analyses the short and long run relationship between budget deficit and trade deficit in some mena countries. the data cover the period from 1971-2000 (and for i.r. iran 1 959-2003).the relationship between these variables will be analyses in short and long run by using johansen cointegration tests, ecm, and granger causality test. the empirical evidence provid...

BACKGROUND Data describing the potential relationship between chronic obstructive pulmonary disease (COPD) and body mass index (BMI) are limited within the Middle East and North Africa (MENA) region. OBJECTIVE To evaluate the distribution of BMI among subjects with COPD in the general population of the MENA region. METHODS This study was a subanalysis of the BREATHE study, a cross-sectional...

OBJECTIVES The objective of this study is to understand the association between HIV and hepatitis C virus (HCV) among people who inject drugs (PWIDs) in the Middle East and North Africa (MENA), and to estimate HIV epidemic potential among PWIDs using HCV prevalence. DESIGN/METHODS Using data from a systematic review of HIV and HCV among PWID in MENA, we conducted two analyses, stratified by H...

Abstract This study investigates the scientific mobility and international collaboration networks in Middle East North Africa (MENA) region between 2008 2017. By using affiliation metadata available publications, we analyze flows linkages. Three complementary approaches allow us to obtain a detailed characterization of mobility. First, uncover main destinations origins mobile scholars for each ...

BACKGROUND The meningococcal serogroup A (MenA) polysaccharide conjugate vaccine used in Sub-Saharan Africa does not prevent disease caused by MenW or MenX strains, which also cause epidemics in the region. We investigated the vaccine-potential of native outer membrane vesicles with over-expressed factor H-binding protein (NOMV-fHbp), which targeted antigens in African meningococcal strains, an...