BACKGROUND The efficacy of epidural anesthesia and analgesia in management of perioperative stress has been established. Perioperative pain management strategies decrease surgical complications and aid recovery. In this study, we aimed to document and compare the efficacy of epidural bupivacaine and intravenous meperidine on recovery of patients with elective abdominal aortic surgery performed ...

BACKGROUND Sedation with midazolam and meperidine is widely used in transesophageal echocardiography. However, no mean dose is established for each individual case. OBJECTIVE To correlate the mean midazolam and meperidine doses for proper sedation for transesophageal echocardiography with age range, body surface area, and left ventricular ejection fraction. METHODS Retrospective study compr...

BACKGROUND Postanaesthetic shivering is one of the most common unpleasant complications in patients. OBJECTIVES The aim of this study was to compare the efficacy of doxapram, ketamine and meperidine in prevention of shivering after anaesthesia. PATIENTS AND METHODS In this randomized, double-blind clinical trial, 120 patients aged between 20 - 45 years old under general anaesthesia were enr...

Mosx OF rile srtrDms of the effects d the commonly used inhalational anaesthetic agents on energy metabolism have been made in patients undergoing surgery. Exceptions are those of Oyama and his group ~-a and of Merin and Associates, ~ who studied effects of anaesthetic agents before the operations began. We have had the opportunity, during pulmonary function studies, 5-r to investigate energy' ...

BACKGROUND The aim was to compare the efficacy and safety of a combination of intramuscular ketorolac and chlorpromazine for the treatment of acute exacerbations of chronic pain with the more commonly used regimen of intramuscular meperidine and promethazine. METHODS Use-effective case series were drawn from a real-life, rural emergency department practice, in which 200 consecutive patients c...

OBJECTIVES To assess the efficacy of intravenous analgesia with meperidine compared to periprostatic plexus infiltration with lidocaine, and safety of periprostatic local anesthesia. MATERIALS AND METHODS A prospective randomized study with 100 patients undergoing first or second prostate biopsy. We distribute patients in two groups, group A (50 patients) which was administered 50 mg of intra...

The serotonin syndrome is a potential side-effect of serotonin-enhancing drugs, including antidepressants such as selective serotonin reuptake inhibitors (SSRIs) and monoamine oxidase inhibitors (MAOIs). We recently reported a genetic mouse model for the serotonin syndrome, as serotonin transporter (SERT)-deficient mice have exaggerated serotonin syndrome behavioural responses to the MAOI trany...

BACKGROUND ERCP practically requires moderate to deep sedation controlled by a combination of benzodiazepine and opiod. Propofol as a sole agent may cause oversedation. A combination (cocktail) of infused propofol, meperidine, and midazolam can reduce the dosage of propofol and we hypothesized that it might decrease the risk of oversedation. We prospectively compare the efficacy, recovery time,...