نتایج جستجو برای: merkel cell polyomavirus
تعداد نتایج: 1686347 فیلتر نتایج به سال:
Merkel cell polyomavirus (MCPyV) is the etiological agent of majority carcinoma (MCC): a rare skin tumor. To improve our understanding role MCPyV in MCCs, detection and analysis DNA transcripts were performed on primary tumors regional lymph nodes from two MCC patients: one metastatic non-metastatic. MCPyV-DNA was searched by quantitative polymerase chain reaction (qPCR), followed amplification...
Merkel cell carcinoma (MCC) is a rare but aggressive skin cancer involving Merkel cells. Recently, a new human polyomavirus was implicated in MCC, being present in 80% of the samples analyzed. In virus-positive MCC, the Merkel cell polyomavirus (MCPyV) is clonally integrated into the patients DNA, and carries mutations in its large T antigen, leading to a truncated protein. In non-symptomatic t...
BACKGROUND While the association of the Merkel cell polyomavirus (MCV) with the neuroendocrine Merkel cell carcinomas (MCC) has been shown recently, it is unknown whether other human polyomaviruses (HPyV) may be associated with neuroendocrine tumours (NETs) of distinct entities. METHODS Using novel, highly sensitive polyomavirus genotyping assays, we evaluated the prevalence of eight distinct...
The polyomavirus family is rapidly expanding with twelve new human viruses identified since 2007. A significant number of the new human polyomaviruses (HPyV) has been found on the skin. Whether these viruses share biological properties and should be grouped together is unknown. Here we investigated the serological behavior of cutaneous HPyVs in a general population. 799 sera from immunocompeten...
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